ENSG00000077274


Homo sapiens

Features
Gene ID: ENSG00000077274
  
Biological name :CAPN6
  
Synonyms : calpain 6 / CAPN6 / Q9Y6Q1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q23
Gene start: 111245103
Gene end: 111270523
  
Corresponding Affymetrix probe sets: 202965_s_at (Human Genome U133 Plus 2.0 Array)   202966_at (Human Genome U133 Plus 2.0 Array)   217387_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317214
NCBI entrez gene - 827     See in Manteia.
OMIM - 300146
RefSeq - NM_014289
RefSeq Peptide - NP_055104
swissprot - Q9Y6Q1
Ensembl - ENSG00000077274
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CAPN6ENSGALG00000008006Gallus gallus
 Capn6ENSMUSG00000067276Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAPN5 / O15484 / calpain 5ENSG0000014926047
CAPN8 / A6NHC0 / calpain 8ENSG0000020369732
CAPN11 / Q9UMQ6 / calpain 11ENSG0000013722531
CAPN3 / P20807 / calpain 3ENSG0000009252931
CAPN1 / P07384 / calpain 1ENSG0000001421630
CAPN2 / P17655 / calpain 2ENSG0000016290930
CAPN9 / O14815 / calpain 9ENSG0000013577329
CAPN12 / Q6ZSI9 / calpain 12ENSG0000018247228
A8MX76 / CAPN14 / calpain 14ENSG0000021471126
CAPN13 / Q6MZZ7 / calpain 13ENSG0000016294924


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR029540  Calpamodulin
 IPR033883  Calpain subdomain III
 IPR033884  Calpain C2 domain
 IPR035892  C2 domain superfamily
 IPR036213  Calpain large subunit, domain III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001578 microtubule bundle formation IEA
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0051493 regulation of cytoskeleton organization ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005876 spindle microtubule IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity TAS
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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