ENSG00000162949


Homo sapiens

Features
Gene ID: ENSG00000162949
  
Biological name :CAPN13
  
Synonyms : calpain 13 / CAPN13 / Q6MZZ7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p23.1
Gene start: 30722771
Gene end: 30820542
  
Corresponding Affymetrix probe sets: 1552801_at (Human Genome U133 Plus 2.0 Array)   229499_at (Human Genome U133 Plus 2.0 Array)   234709_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295055
Ensembl peptide - ENSP00000403180
Ensembl peptide - ENSP00000416191
Ensembl peptide - ENSP00000440723
NCBI entrez gene - 92291     See in Manteia.
OMIM - 610228
RefSeq - XM_017005266
RefSeq - XM_011533161
RefSeq - XM_011533163
RefSeq - XM_017005264
RefSeq - XM_017005265
RefSeq - NM_144575
RefSeq - XM_011533159
RefSeq - XM_011533160
RefSeq Peptide - NP_653176
swissprot - H7C1Z4
swissprot - F5GYA7
swissprot - Q6MZZ7
Ensembl - ENSG00000162949
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-202f3.3ENSDARG00000052917Danio rerio
 si:ch211-202f3.4ENSDARG00000091723Danio rerio
 zgc:136872ENSDARG00000008553Danio rerio
 zgc:162184ENSDARG00000077217Danio rerio
 CAPN13ENSGALG00000020084Gallus gallus
 Capn13ENSMUSG00000043705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A8MX76 / CAPN14 / calpain 14ENSG0000021471134
CAPN1 / P07384 / calpain 1ENSG0000001421634
CAPN11 / Q9UMQ6 / calpain 11ENSG0000013722534
CAPN8 / A6NHC0 / calpain 8ENSG0000020369733
CAPN3 / P20807 / calpain 3ENSG0000009252932
CAPN12 / Q6ZSI9 / calpain 12ENSG0000018247231
CAPN2 / P17655 / calpain 2ENSG0000016290931
CAPN9 / O14815 / calpain 9ENSG0000013577331
CAPN5 / O15484 / calpain 5ENSG0000014926024
CAPN6 / Q9Y6Q1 / calpain 6ENSG0000007727423


Protein motifs (from Interpro)
Interpro ID Name
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR011992  EF-hand domain pair
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022684  Peptidase C2, calpain family
 IPR029544  Calpain-13/Calpain-C
 IPR036213  Calpain large subunit, domain III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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