ENSMUSG00000067276


Mus musculus

Features
Gene ID: ENSMUSG00000067276
  
Biological name :Capn6
  
Synonyms : Calpain-6 / Capn6 / O35646
  
Possible biological names infered from orthology : Q9Y6Q1
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F2
Gene start: 143802231
Gene end: 143827414
  
Corresponding Affymetrix probe sets: 10607143 (MoGene1.0st)   1421952_at (Mouse Genome 430 2.0 Array)   1450429_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000084573
NCBI entrez gene - 12338     See in Manteia.
MGI - MGI:1100850
RefSeq - NM_007603
RefSeq Peptide - NP_031629
swissprot - O35646
Ensembl - ENSMUSG00000067276
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CAPN6ENSGALG00000008006Gallus gallus
 CAPN6ENSG00000077274Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Capn5 / O08688 / Calpain-5 / O15484*ENSMUSG0000003554746
Capn3 / Q64691 / Calpain-3 / P20807*ENSMUSG0000007911031
Capn1 / O35350 / Calpain-1 catalytic subunit / P07384* / calpain 1*ENSMUSG0000002494231
Capn2 / O08529 / Calpain-2 catalytic subunit / P17655* / calpain 2*ENSMUSG0000002650930
Capn8 / Q91VA3 / Calpain-8 / A6NHC0*ENSMUSG0000003859930
Capn9 / Q9D805 / Calpain-9 / O14815*ENSMUSG0000003198129
Capn11 / Q6J756 / Calpain-11 / Q9UMQ6*ENSMUSG0000005862628
Capn12 / calpain 12 / Q6ZSI9*ENSMUSG0000005408328
Capn13 / Q3UW68 / Calpain-13 / Q6MZZ7*ENSMUSG0000004370524


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR029540  Calpamodulin
 IPR033883  Calpain subdomain III
 IPR033884  Calpain C2 domain
 IPR035892  C2 domain superfamily
 IPR036213  Calpain large subunit, domain III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001578 microtubule bundle formation IMP
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0051493 regulation of cytoskeleton organization IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005876 spindle microtubule IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IDA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000729 abnormal myogenesis "anomaly in embryonic formation of muscle cells or fibers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Topbp1tm1.1Zqw/Topbp1tm1.1Zqw
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor

 MP:0004136 abnormal tongue muscle morphology "anomalous structure or development of the muscular portion of the tongue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Topbp1tm1.1Zqw/Topbp1tm1.1Zqw
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor

 MP:0013237 abnormal skeletal muscle regeneration "anomaly in the ability to repair skeletal muscle after injury or disease" [MGI:csmith]
Show

Allelic Composition: Topbp1tm1.1Zqw/Topbp1tm1.1Zqw
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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