ENSMUSG00000058626


Mus musculus

Features
Gene ID: ENSMUSG00000058626
  
Biological name :Capn11
  
Synonyms : Calpain-11 / Capn11 / Q6J756
  
Possible biological names infered from orthology : Q9UMQ6
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B3
Gene start: 45630204
Gene end: 45659325
  
Corresponding Affymetrix probe sets: 10451145 (MoGene1.0st)   1445698_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113132
Ensembl peptide - ENSMUSP00000119679
NCBI entrez gene - 268958     See in Manteia.
MGI - MGI:1352490
RefSeq - XM_017317486
RefSeq - NM_001013767
RefSeq - XM_011246479
RefSeq Peptide - NP_001013789
swissprot - Q6J756
swissprot - A0A0A0MQJ1
Ensembl - ENSMUSG00000058626
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capn1aENSDARG00000052702Danio rerio
 capn1bENSDARG00000052748Danio rerio
 CAPN11ENSGALG00000010186Gallus gallus
 CAPN11ENSG00000137225Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Capn1 / O35350 / Calpain-1 catalytic subunit / P07384* / calpain 1*ENSMUSG0000002494251
Capn2 / O08529 / Calpain-2 catalytic subunit / P17655* / calpain 2*ENSMUSG0000002650950
Capn8 / Q91VA3 / Calpain-8 / A6NHC0*ENSMUSG0000003859947
Capn3 / Q64691 / Calpain-3 / P20807*ENSMUSG0000007911046
Capn9 / Q9D805 / Calpain-9 / O14815*ENSMUSG0000003198144
Capn12 / calpain 12 / Q6ZSI9*ENSMUSG0000005408339
Capn13 / Q3UW68 / Calpain-13 / Q6MZZ7*ENSMUSG0000004370530
Capn5 / O08688 / Calpain-5 / O15484*ENSMUSG0000003554730
Capn6 / O35646 / Calpain-6 / Q9Y6Q1*ENSMUSG0000006727625


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR033883  Calpain subdomain III
 IPR036213  Calpain large subunit, domain III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0001669 acrosomal vesicle IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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