ENSMUSG00000054083


Mus musculus

Features
Gene ID: ENSMUSG00000054083
  
Biological name :Capn12
  
Synonyms : calpain 12 / Capn12
  
Possible biological names infered from orthology : Q6ZSI9
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B1
Gene start: 28881422
Gene end: 28893563
  
Corresponding Affymetrix probe sets: 10551644 (MoGene1.0st)   1449970_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000069055
NCBI entrez gene - 60594     See in Manteia.
MGI - MGI:1891369
RefSeq - XM_006540253
RefSeq - NM_001110807
RefSeq - XM_006540252
RefSeq Peptide - NP_001104277
swissprot - E9QL26
Ensembl - ENSMUSG00000054083
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capn12ENSDARG00000010758Danio rerio
 CAPN12ENSG00000182472Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Capn1 / O35350 / Calpain-1 catalytic subunit / P07384* / calpain 1*ENSMUSG0000002494243
Capn2 / O08529 / Calpain-2 catalytic subunit / P17655* / calpain 2*ENSMUSG0000002650941
Capn8 / Q91VA3 / Calpain-8 / A6NHC0*ENSMUSG0000003859941
Capn9 / Q9D805 / Calpain-9 / O14815*ENSMUSG0000003198139
Capn3 / Q64691 / Calpain-3 / P20807*ENSMUSG0000007911038
Capn11 / Q6J756 / Calpain-11 / Q9UMQ6*ENSMUSG0000005862638
Capn13 / Q3UW68 / Calpain-13 / Q6MZZ7*ENSMUSG0000004370527
Capn5 / O08688 / Calpain-5 / O15484*ENSMUSG0000003554727
Capn6 / O35646 / Calpain-6 / Q9Y6Q1*ENSMUSG0000006727625


Protein motifs (from Interpro)
Interpro ID Name
 IPR000169  Cysteine peptidase, cysteine active site
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR029545  Calpain-12
 IPR033883  Calpain subdomain III
 IPR036213  Calpain large subunit, domain III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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