ENSG00000136098


Homo sapiens

Features
Gene ID: ENSG00000136098
  
Biological name :NEK3
  
Synonyms : NEK3 / NIMA related kinase 3 / P51956
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q14.3
Gene start: 52132639
Gene end: 52159861
  
Corresponding Affymetrix probe sets: 211089_s_at (Human Genome U133 Plus 2.0 Array)   213116_at (Human Genome U133 Plus 2.0 Array)   239539_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000483058
Ensembl peptide - ENSP00000487230
Ensembl peptide - ENSP00000484594
Ensembl peptide - ENSP00000484443
Ensembl peptide - ENSP00000484086
Ensembl peptide - ENSP00000447995
Ensembl peptide - ENSP00000449679
Ensembl peptide - ENSP00000480328
Ensembl peptide - ENSP00000481533
NCBI entrez gene - 4752     See in Manteia.
OMIM - 604044
RefSeq - NM_152720
RefSeq - NM_001146099
RefSeq - NM_002498
RefSeq Peptide - NP_002489
RefSeq Peptide - NP_001139571
RefSeq Peptide - NP_689933
swissprot - P51956
swissprot - A0A087X030
swissprot - A0A087WY58
swissprot - F8VTT4
swissprot - F8VV00
swissprot - A0A087X203
Ensembl - ENSG00000136098
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NEK3ENSDARG00000058869Danio rerio
 NEK3ENSGALG00000017024Gallus gallus
 Nek3ENSMUSG00000031478Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEK1 / Q96PY6 / NIMA related kinase 1ENSG0000013760143
NEK5 / Q6P3R8 / NIMA related kinase 5ENSG0000019716836
NEK4 / P51957 / NIMA related kinase 4ENSG0000011490428
NEK2 / P51955 / NIMA related kinase 2ENSG0000011765026
NEK9 / Q8TD19 / NIMA related kinase 9ENSG0000011963826
NEK11 / Q8NG66 / NIMA related kinase 11ENSG0000011467025
NEK8 / Q86SG6 / NIMA related kinase 8ENSG0000016060224
NEK6 / Q9HC98 / NIMA related kinase 6ENSG0000011940820
NEK7 / Q8TDX7 / NIMA related kinase 7ENSG0000015141419


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle NAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030010 establishment of cell polarity IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0090043 regulation of tubulin deacetylation IEA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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