ENSMUSG00000031478


Mus musculus

Features
Gene ID: ENSMUSG00000031478
  
Biological name :Nek3
  
Synonyms : Nek3 / Q9R0A5 / Serine/threonine-protein kinase Nek3
  
Possible biological names infered from orthology : NIMA related kinase 3 / P51956
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A2
Gene start: 22128283
Gene end: 22166435
  
Corresponding Affymetrix probe sets: 10577492 (MoGene1.0st)   1418947_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033865
Ensembl peptide - ENSMUSP00000106358
Ensembl peptide - ENSMUSP00000136876
NCBI entrez gene - 23954     See in Manteia.
MGI - MGI:1344371
RefSeq - XM_006509111
RefSeq - NM_001162947
RefSeq - NM_011848
RefSeq Peptide - NP_001156419
RefSeq Peptide - NP_035978
swissprot - Q9R0A5
swissprot - F8WGD4
Ensembl - ENSMUSG00000031478
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NEK3ENSDARG00000058869Danio rerio
 NEK3ENSGALG00000017024Gallus gallus
 NEK3ENSG00000136098Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nek1 / P51954 / NIMA (never in mitosis gene a)-related expressed kinase 1 / Q96PY6* / NIMA related kinase 1*ENSMUSG0000003164439
Nek5 / Q7TSC3 / Mus musculus NIMA (never in mitosis a)-related expressed kinase 5 (Nek5), transcript variant 2, mRNA. / Q6P3R8* / NIMA related kinase 5*ENSMUSG0000003773835
Nek2 / O35942 / Serine/threonine-protein kinase Nek2 / P51955* / NIMA related kinase 2*ENSMUSG0000002662227
Nek4 / NIMA related kinase 4 / P51957*ENSMUSG0000002191826
Nek9 / Q8K1R7 / Serine/threonine-protein kinase Nek9 / Q8TD19* / NIMA related kinase 9*ENSMUSG0000003429026
Nek11 / Q8C0Q4 / Serine/threonine-protein kinase Nek11 / Q8NG66* / NIMA related kinase 11*ENSMUSG0000003503225
Nek8 / Q91ZR4 / Serine/threonine-protein kinase Nek8 / Q86SG6* / NIMA related kinase 8*ENSMUSG0000001740523
Nek6 / Q9ES70 / Serine/threonine-protein kinase Nek6 / Q9HC98* / NIMA related kinase 6*ENSMUSG0000002674921
Nek7 / Q9ES74 / Serine/threonine-protein kinase Nek7 / Q8TDX7* / NIMA related kinase 7*ENSMUSG0000002639320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030010 establishment of cell polarity IMP
 biological_processGO:0048812 neuron projection morphogenesis IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0090043 regulation of tubulin deacetylation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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