ENSMUSG00000035032


Mus musculus

Features
Gene ID: ENSMUSG00000035032
  
Biological name :Nek11
  
Synonyms : Nek11 / Q8C0Q4 / Serine/threonine-protein kinase Nek11
  
Possible biological names infered from orthology : NIMA related kinase 11 / Q8NG66
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F1
Gene start: 105162156
Gene end: 105395524
  
Corresponding Affymetrix probe sets: 10596327 (MoGene1.0st)   1441525_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135837
Ensembl peptide - ENSMUSP00000038611
Ensembl peptide - ENSMUSP00000116761
Ensembl peptide - ENSMUSP00000116864
NCBI entrez gene - 208583     See in Manteia.
MGI - MGI:2442276
RefSeq - XM_017313259
RefSeq - XM_006511680
RefSeq - XM_006511682
RefSeq - XM_006511685
RefSeq - XM_006511686
RefSeq - XM_006511687
RefSeq - NM_172461
RefSeq - XM_006511679
RefSeq Peptide - NP_766049
swissprot - H3BLL8
swissprot - D6RH85
swissprot - D3Z1E7
swissprot - Q8C0Q4
Ensembl - ENSMUSG00000035032
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nek11ENSDARG00000087564Danio rerio
 NEK11ENSGALG00000037242Gallus gallus
 NEK11ENSG00000114670Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nek4 / NIMA related kinase 4 / P51957*ENSMUSG0000002191825
Nek1 / P51954 / NIMA (never in mitosis gene a)-related expressed kinase 1 / Q96PY6* / NIMA related kinase 1*ENSMUSG0000003164424
Nek5 / Q7TSC3 / Mus musculus NIMA (never in mitosis a)-related expressed kinase 5 (Nek5), transcript variant 2, mRNA. / Q6P3R8* / NIMA related kinase 5*ENSMUSG0000003773822
Nek3 / Q9R0A5 / Serine/threonine-protein kinase Nek3 / P51956* / NIMA related kinase 3*ENSMUSG0000003147820
Nek9 / Q8K1R7 / Serine/threonine-protein kinase Nek9 / Q8TD19* / NIMA related kinase 9*ENSMUSG0000003429019
Nek8 / Q91ZR4 / Serine/threonine-protein kinase Nek8 / Q86SG6* / NIMA related kinase 8*ENSMUSG0000001740519
Nek2 / O35942 / Serine/threonine-protein kinase Nek2 / P51955* / NIMA related kinase 2*ENSMUSG0000002662218
Nek7 / Q9ES74 / Serine/threonine-protein kinase Nek7 / Q8TDX7* / NIMA related kinase 7*ENSMUSG0000002639314
Nek6 / Q9ES70 / Serine/threonine-protein kinase Nek6 / Q9HC98* / NIMA related kinase 6*ENSMUSG0000002674913


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016572 histone phosphorylation IEA
 biological_processGO:0031573 intra-S DNA damage checkpoint IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0044772 mitotic cell cycle phase transition IEA
 biological_processGO:1901990 regulation of mitotic cell cycle phase transition IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Ncoa3tm1b(EUCOMM)Wtsi/Ncoa3+
Genetic Background: C57BL/6N-Ncoa3tm1b(EUCOMM)Wtsi/H

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ncoa3tm1b(EUCOMM)Wtsi/Ncoa3+
Genetic Background: C57BL/6N-Ncoa3tm1b(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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