ENSMUSG00000037738


Mus musculus

Features
Gene ID: ENSMUSG00000037738
  
Biological name :Nek5
  
Synonyms : Mus musculus NIMA (never in mitosis a)-related expressed kinase 5 (Nek5), transcript variant 2, mRNA. / Nek5 / Q7TSC3
  
Possible biological names infered from orthology : NIMA related kinase 5 / Q6P3R8
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A2
Gene start: 22073616
Gene end: 22125053
  
Corresponding Affymetrix probe sets: 10577471 (MoGene1.0st)   1444163_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126705
Ensembl peptide - ENSMUSP00000147849
Ensembl peptide - ENSMUSP00000148211
NCBI entrez gene - 330721     See in Manteia.
MGI - MGI:2142824
RefSeq - XM_017312864
RefSeq - NM_001347318
RefSeq - NM_177898
RefSeq - XM_011242146
RefSeq - XM_011242147
RefSeq - XM_011242148
RefSeq - XM_017312863
RefSeq - XM_006509154
RefSeq - XM_006509155
RefSeq - XM_006509159
RefSeq - XM_006509160
RefSeq - XM_011242143
RefSeq - XM_011242144
RefSeq - XM_011242145
RefSeq Peptide - NP_001334247
RefSeq Peptide - NP_808566
swissprot - Q7TSC3
swissprot - A0A1B0GS95
Ensembl - ENSMUSG00000037738
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NEK5ENSGALG00000017023Gallus gallus
 NEK5ENSG00000197168Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nek1 / P51954 / NIMA (never in mitosis gene a)-related expressed kinase 1 / Q96PY6* / NIMA related kinase 1*ENSMUSG0000003164440
Nek3 / Q9R0A5 / Serine/threonine-protein kinase Nek3 / P51956* / NIMA related kinase 3*ENSMUSG0000003147828
Nek9 / Q8K1R7 / Serine/threonine-protein kinase Nek9 / Q8TD19* / NIMA related kinase 9*ENSMUSG0000003429024
Nek11 / Q8C0Q4 / Serine/threonine-protein kinase Nek11 / Q8NG66* / NIMA related kinase 11*ENSMUSG0000003503222
Nek8 / Q91ZR4 / Serine/threonine-protein kinase Nek8 / Q86SG6* / NIMA related kinase 8*ENSMUSG0000001740522
Nek4 / NIMA related kinase 4 / P51957*ENSMUSG0000002191821
Nek2 / O35942 / Serine/threonine-protein kinase Nek2 / P51955* / NIMA related kinase 2*ENSMUSG0000002662221
Nek7 / Q9ES74 / Serine/threonine-protein kinase Nek7 / Q8TDX7* / NIMA related kinase 7*ENSMUSG0000002639315
Nek6 / Q9ES70 / Serine/threonine-protein kinase Nek6 / Q9HC98* / NIMA related kinase 6*ENSMUSG0000002674914


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0051155 positive regulation of striated muscle cell differentiation IDA
 biological_processGO:2001056 positive regulation of cysteine-type endopeptidase activity IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006325 impaired hearing "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Myo7ampc142H/Myo7ampc142H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr