ENSG00000136457


Homo sapiens

Features
Gene ID: ENSG00000136457
  
Biological name :CHAD
  
Synonyms : CHAD / chondroadherin / O15335
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.33
Gene start: 50464496
Gene end: 50468966
  
Corresponding Affymetrix probe sets: 206869_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258969
Ensembl peptide - ENSP00000423812
Ensembl peptide - ENSP00000425672
NCBI entrez gene - 1101     See in Manteia.
OMIM - 602178
RefSeq - XM_011524214
RefSeq - NM_001267
RefSeq Peptide - NP_001258
swissprot - O15335
swissprot - H0YA03
Ensembl - ENSG00000136457
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chadENSDARG00000045071Danio rerio
 CHADENSGALG00000019761Gallus gallus
 ChadENSMUSG00000039084Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHADL / Q6NUI6 / chondroadherin likeENSG0000010039941
IGFALS / P35858 / insulin like growth factor binding protein acid labile subunitENSG0000009976925
CPN2 / P22792 / carboxypeptidase N subunit 2ENSG0000017877224
LRRC15 / Q8TF66 / leucine rich repeat containing 15ENSG0000017206124
GP5 / P40197 / glycoprotein V plateletENSG0000017873223
LRRC70 / Q7Z2Q7 / leucine rich repeat containing 70ENSG0000018610520
TRIL / Q7L0X0 / TLR4 interactor with leucine rich repeatsENSG0000025569019
NYX / Q9GZU5 / nyctalopinENSG0000018893719
LRRTM2 / O43300 / leucine rich repeat transmembrane neuronal 2ENSG0000014600615
LRRTM3 / Q86VH5 / leucine rich repeat transmembrane neuronal 3ENSG0000019873914
LRRTM4 / Q86VH4 / leucine rich repeat transmembrane neuronal 4ENSG0000017620414
LRRTM1 / Q86UE6 / leucine rich repeat transmembrane neuronal 1ENSG0000016295113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0060348 bone development IEA
 biological_processGO:1900155 negative regulation of bone trabecula formation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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