ENSG00000146006


Homo sapiens

Features
Gene ID: ENSG00000146006
  
Biological name :LRRTM2
  
Synonyms : leucine rich repeat transmembrane neuronal 2 / LRRTM2 / O43300
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.2
Gene start: 138868923
Gene end: 138875368
  
Corresponding Affymetrix probe sets: 206408_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000274711
Ensembl peptide - ENSP00000430902
Ensembl peptide - ENSP00000428398
NCBI entrez gene - 26045     See in Manteia.
OMIM - 610868
RefSeq - NM_015564
RefSeq Peptide - NP_056379
swissprot - E5RIQ2
swissprot - E5RHE5
swissprot - O43300
Ensembl - ENSG00000146006
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrtm2ENSDARG00000071374Danio rerio
 LRRTM2ENSGALG00000002455Gallus gallus
 Lrrtm2ENSMUSG00000071862Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRTM1 / Q86UE6 / leucine rich repeat transmembrane neuronal 1ENSG0000016295147
LRRTM4 / Q86VH4 / leucine rich repeat transmembrane neuronal 4ENSG0000017620443
LRRTM3 / Q86VH5 / leucine rich repeat transmembrane neuronal 3ENSG0000019873943
TRIL / Q7L0X0 / TLR4 interactor with leucine rich repeatsENSG0000025569023
LRRC15 / Q8TF66 / leucine rich repeat containing 15ENSG0000017206121
IGFALS / P35858 / insulin like growth factor binding protein acid labile subunitENSG0000009976920
GP5 / P40197 / glycoprotein V plateletENSG0000017873220
CHADL / Q6NUI6 / chondroadherin likeENSG0000010039920
LRRC70 / Q7Z2Q7 / leucine rich repeat containing 70ENSG0000018610519
CPN2 / P22792 / carboxypeptidase N subunit 2ENSG0000017877219
NYX / Q9GZU5 / nyctalopinENSG0000018893717
CHAD / O15335 / chondroadherinENSG0000013645710


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002091 negative regulation of receptor internalization IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0060076 excitatory synapse IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042043 neurexin family protein binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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