ENSG00000198739


Homo sapiens

Features
Gene ID: ENSG00000198739
  
Biological name :LRRTM3
  
Synonyms : leucine rich repeat transmembrane neuronal 3 / LRRTM3 / Q86VH5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q21.3
Gene start: 66926006
Gene end: 67099830
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000355187
NCBI entrez gene - 347731     See in Manteia.
OMIM - 610869
RefSeq - NM_178011
RefSeq Peptide - NP_821079
swissprot - Q86VH5
Ensembl - ENSG00000198739
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRRTM3ENSGALG00000002864Gallus gallus
 Lrrtm3ENSMUSG00000042846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRTM4 / Q86VH4 / leucine rich repeat transmembrane neuronal 4ENSG0000017620460
LRRTM1 / Q86UE6 / leucine rich repeat transmembrane neuronal 1ENSG0000016295140
LRRTM2 / O43300 / leucine rich repeat transmembrane neuronal 2ENSG0000014600638
TRIL / Q7L0X0 / TLR4 interactor with leucine rich repeatsENSG0000025569020
CHADL / Q6NUI6 / chondroadherin likeENSG0000010039919
CPN2 / P22792 / carboxypeptidase N subunit 2ENSG0000017877218
LRRC15 / Q8TF66 / leucine rich repeat containing 15ENSG0000017206118
LRRC70 / Q7Z2Q7 / leucine rich repeat containing 70ENSG0000018610518
GP5 / P40197 / glycoprotein V plateletENSG0000017873217
IGFALS / P35858 / insulin like growth factor binding protein acid labile subunitENSG0000009976917
NYX / Q9GZU5 / nyctalopinENSG0000018893717
CHAD / O15335 / chondroadherinENSG000001364579


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:1902004 positive regulation of amyloid-beta formation IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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