ENSMUSG00000042846


Mus musculus

Features
Gene ID: ENSMUSG00000042846
  
Biological name :Lrrtm3
  
Synonyms : Leucine-rich repeat transmembrane neuronal protein 3 / Lrrtm3 / Q8BZ81
  
Possible biological names infered from orthology : leucine rich repeat transmembrane neuronal 3 / Q86VH5
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B4
Gene start: 63928472
Gene end: 64090277
  
Corresponding Affymetrix probe sets: 10369752 (MoGene1.0st)   1434759_at (Mouse Genome 430 2.0 Array)   1434760_at (Mouse Genome 430 2.0 Array)   1434761_at (Mouse Genome 430 2.0 Array)   1440112_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101079
NCBI entrez gene - 216028     See in Manteia.
MGI - MGI:2389177
RefSeq - NM_178678
RefSeq Peptide - NP_848793
swissprot - Q8BZ81
Ensembl - ENSMUSG00000042846
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRRTM3ENSGALG00000002864Gallus gallus
 LRRTM3ENSG00000198739Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lrrtm4 / Q80XG9 / Mus musculus leucine rich repeat transmembrane neuronal 4 (Lrrtm4), transcript variant 4, mRNA. / Q86VH4* / leucine rich repeat transmembrane neuronal 4*ENSMUSG0000005258159
Lrrtm1 / Q8K377 / Leucine-rich repeat transmembrane neuronal protein 1 / Q86UE6* / leucine rich repeat transmembrane neuronal 1*ENSMUSG0000006078040
Lrrtm2 / Q8BGA3 / Leucine-rich repeat transmembrane neuronal protein 2 / O43300* / leucine rich repeat transmembrane neuronal 2*ENSMUSG0000007186238
Tril / Q9DBY4 / TLR4 interactor with leucine rich repeats / Q7L0X0*ENSMUSG0000004349620
Gp5 / glycoprotein V platelet / P40197*ENSMUSG0000004795318
Chadl / E9Q7T7 / Chondroadherin-like protein / Q6NUI6* / chondroadherin like*ENSMUSG0000006376518
Lrrc15 / Q80X72 / Leucine-rich repeat-containing protein 15 / Q8TF66* / leucine rich repeat containing 15*ENSMUSG0000005231618
Igfals / insulin-like growth factor binding protein, acid labile subunit / P35858*ENSMUSG0000004607017
Cpn2 / Q9DBB9 / Carboxypeptidase N subunit 2 / P22792*ENSMUSG0000002317617
Nyx / P83503 / Nyctalopin / Q9GZU5*ENSMUSG0000005122816
Chad / O55226 / Chondroadherin / O15335*ENSMUSG000000390848


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0051965 positive regulation of synapse assembly IDA
 biological_processGO:1902004 positive regulation of amyloid-beta formation IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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