ENSMUSG00000052316


Mus musculus

Features
Gene ID: ENSMUSG00000052316
  
Biological name :Lrrc15
  
Synonyms : Leucine-rich repeat-containing protein 15 / Lrrc15 / Q80X72
  
Possible biological names infered from orthology : leucine rich repeat containing 15 / Q8TF66
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B2
Gene start: 30269302
Gene end: 30283256
  
Corresponding Affymetrix probe sets: 10438904 (MoGene1.0st)   1436055_at (Mouse Genome 430 2.0 Array)   1453214_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066777
NCBI entrez gene - 74488     See in Manteia.
MGI - MGI:1921738
RefSeq - NM_028973
RefSeq Peptide - NP_083249
swissprot - Q80X72
Ensembl - ENSMUSG00000052316
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc15ENSDARG00000070792Danio rerio
 LRRC15ENSGALG00000046461Gallus gallus
 LRRC15ENSG00000172061Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gp5 / glycoprotein V platelet / P40197*ENSMUSG0000004795330
Cpn2 / Q9DBB9 / Carboxypeptidase N subunit 2 / P22792*ENSMUSG0000002317626
Chadl / E9Q7T7 / Chondroadherin-like protein / Q6NUI6* / chondroadherin like*ENSMUSG0000006376525
Igfals / insulin-like growth factor binding protein, acid labile subunit / P35858*ENSMUSG0000004607024
Tril / Q9DBY4 / TLR4 interactor with leucine rich repeats / Q7L0X0*ENSMUSG0000004349624
Nyx / P83503 / Nyctalopin / Q9GZU5*ENSMUSG0000005122820
Lrrtm4 / Q80XG9 / Mus musculus leucine rich repeat transmembrane neuronal 4 (Lrrtm4), transcript variant 4, mRNA. / Q86VH4* / leucine rich repeat transmembrane neuronal 4*ENSMUSG0000005258119
Lrrtm3 / Q8BZ81 / Leucine-rich repeat transmembrane neuronal protein 3 / Q86VH5* / leucine rich repeat transmembrane neuronal 3*ENSMUSG0000004284618
Lrrtm2 / Q8BGA3 / Leucine-rich repeat transmembrane neuronal protein 2 / O43300* / leucine rich repeat transmembrane neuronal 2*ENSMUSG0000007186218
Chad / O55226 / Chondroadherin / O15335*ENSMUSG0000003908415
Lrrtm1 / Q8K377 / Leucine-rich repeat transmembrane neuronal protein 1 / Q86UE6* / leucine rich repeat transmembrane neuronal 1*ENSMUSG0000006078015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0046813 receptor-mediated virion attachment to host cell IEA
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0001968 fibronectin binding IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0043236 laminin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003898 abnormal QRS complex "anomaly in the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarise prior to their contraction" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Jam3tm1.1(KOMP)Vlcg/Jam3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Jam3tm1.1(KOMP)Vlcg/J

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Jam3tm1.1(KOMP)Vlcg/Jam3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Jam3tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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