ENSMUSG00000051228


Mus musculus

Features
Gene ID: ENSMUSG00000051228
  
Biological name :Nyx
  
Synonyms : Nyctalopin / Nyx / P83503
  
Possible biological names infered from orthology : Q9GZU5
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A1.1
Gene start: 13466110
Gene end: 13489313
  
Corresponding Affymetrix probe sets: 10598743 (MoGene1.0st)   1446344_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056313
NCBI entrez gene - 236690     See in Manteia.
MGI - MGI:2448607
RefSeq - XM_006527614
RefSeq - NM_173415
RefSeq - XM_006527612
RefSeq - XM_006527613
RefSeq Peptide - NP_775591
swissprot - P83503
Ensembl - ENSMUSG00000051228
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nyxENSDARG00000061791Danio rerio
 NYXENSGALG00000016228Gallus gallus
 NYXENSG00000188937Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Igfals / insulin-like growth factor binding protein, acid labile subunit / P35858*ENSMUSG0000004607028
Chadl / E9Q7T7 / Chondroadherin-like protein / Q6NUI6* / chondroadherin like*ENSMUSG0000006376527
Tril / Q9DBY4 / TLR4 interactor with leucine rich repeats / Q7L0X0*ENSMUSG0000004349625
Lrrc15 / Q80X72 / Leucine-rich repeat-containing protein 15 / Q8TF66* / leucine rich repeat containing 15*ENSMUSG0000005231625
Gp5 / glycoprotein V platelet / P40197*ENSMUSG0000004795324
Cpn2 / Q9DBB9 / Carboxypeptidase N subunit 2 / P22792*ENSMUSG0000002317623
Lrrtm4 / Q80XG9 / Mus musculus leucine rich repeat transmembrane neuronal 4 (Lrrtm4), transcript variant 4, mRNA. / Q86VH4* / leucine rich repeat transmembrane neuronal 4*ENSMUSG0000005258120
Lrrtm3 / Q8BZ81 / Leucine-rich repeat transmembrane neuronal protein 3 / Q86VH5* / leucine rich repeat transmembrane neuronal 3*ENSMUSG0000004284620
Lrrtm1 / Q8K377 / Leucine-rich repeat transmembrane neuronal protein 1 / Q86UE6* / leucine rich repeat transmembrane neuronal 1*ENSMUSG0000006078019
Lrrtm2 / Q8BGA3 / Leucine-rich repeat transmembrane neuronal protein 2 / O43300* / leucine rich repeat transmembrane neuronal 2*ENSMUSG0000007186218
Chad / O55226 / Chondroadherin / O15335*ENSMUSG0000003908414


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002090 abnormal vision "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mapk1tm2Moga/Mapk1tm2Moga
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mapk1tm2Moga/Mapk1tm2Moga
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Nyxnob/Nyxnob
Genetic Background: involves: BALB/cGr

Allelic Composition: Nyxnob/Y
Genetic Background: involves: BALB/cGr

Allelic Composition: Nyxnob/Nyx+
Genetic Background: involves: BALB/cGr

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mapk1tm2Moga/Mapk1tm2Moga
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Nyxnob/Nyxnob
Genetic Background: involves: BALB/cGr

Allelic Composition: Nyxnob/Y
Genetic Background: involves: BALB/cGr

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Mapk1tm2Moga/Mapk1tm2Moga
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010749 absent visual evoked potential "absence of a characteristic electroencephalographic pattern recorded from the occipital area generated in response to retinal stimulation such as flashing lights or inverting a contrasting image; absence may indicate blindness" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mapk1tm2Moga/Mapk1tm2Moga
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr