ENSG00000162951


Homo sapiens

Features
Gene ID: ENSG00000162951
  
Biological name :LRRTM1
  
Synonyms : leucine rich repeat transmembrane neuronal 1 / LRRTM1 / Q86UE6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p12
Gene start: 80288351
Gene end: 80304749
  
Corresponding Affymetrix probe sets: 238815_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000389473
Ensembl peptide - ENSP00000415368
Ensembl peptide - ENSP00000414523
Ensembl peptide - ENSP00000404557
Ensembl peptide - ENSP00000393562
Ensembl peptide - ENSP00000295057
Ensembl peptide - ENSP00000386646
NCBI entrez gene - 347730     See in Manteia.
OMIM - 610867
RefSeq - XM_017003987
RefSeq - NM_178839
RefSeq - XM_017003986
RefSeq Peptide - NP_849161
swissprot - C9JPM9
swissprot - Q86UE6
swissprot - C9JEE2
swissprot - C9JF97
Ensembl - ENSG00000162951
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrtm1ENSDARG00000052713Danio rerio
 LRRTM1ENSGALG00000015967Gallus gallus
 Lrrtm1ENSMUSG00000060780Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRTM2 / O43300 / leucine rich repeat transmembrane neuronal 2ENSG0000014600647
LRRTM3 / Q86VH5 / leucine rich repeat transmembrane neuronal 3ENSG0000019873945
LRRTM4 / Q86VH4 / leucine rich repeat transmembrane neuronal 4ENSG0000017620445
TRIL / Q7L0X0 / TLR4 interactor with leucine rich repeatsENSG0000025569022
CHADL / Q6NUI6 / chondroadherin likeENSG0000010039920
IGFALS / P35858 / insulin like growth factor binding protein acid labile subunitENSG0000009976919
GP5 / P40197 / glycoprotein V plateletENSG0000017873219
LRRC70 / Q7Z2Q7 / leucine rich repeat containing 70ENSG0000018610518
NYX / Q9GZU5 / nyctalopinENSG0000018893718
LRRC15 / Q8TF66 / leucine rich repeat containing 15ENSG0000017206117
CPN2 / P22792 / carboxypeptidase N subunit 2ENSG0000017877217
CHAD / O15335 / chondroadherinENSG000001364579


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002091 negative regulation of receptor internalization IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0035418 protein localization to synapse IEA
 biological_processGO:0035640 exploration behavior IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030426 growth cone IDA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0060076 excitatory synapse IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr