ENSG00000136940


Homo sapiens

Features
Gene ID: ENSG00000136940
  
Biological name :PDCL
  
Synonyms : PDCL / phosducin like / Q13371
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q33.2
Gene start: 122798389
Gene end: 122828631
  
Corresponding Affymetrix probe sets: 204448_s_at (Human Genome U133 Plus 2.0 Array)   204449_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000259467
Ensembl peptide - ENSP00000377826
Ensembl peptide - ENSP00000397984
NCBI entrez gene - 5082     See in Manteia.
OMIM - 604421
RefSeq - XM_017014785
RefSeq - NM_005388
RefSeq Peptide - NP_005379
swissprot - H0Y3M0
swissprot - Q13371
swissprot - H0Y5D3
Ensembl - ENSG00000136940
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdclENSDARG00000009480Danio rerio
 PDCLENSGALG00000001275Gallus gallus
 PdclENSMUSG00000009030Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDC / P20941 / phosducinENSG0000011670337


Protein motifs (from Interpro)
Interpro ID Name
 IPR001200  Phosducin
 IPR023196  Phosducin, N-terminal domain superfamily
 IPR024253  Phosducin, thioredoxin-like domain
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway TAS
 biological_processGO:0008616 queuosine biosynthetic process IBA
 biological_processGO:0045880 positive regulation of smoothened signaling pathway IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0061084 negative regulation of protein refolding IEA
 biological_processGO:1902605 heterotrimeric G-protein complex assembly IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008479 queuine tRNA-ribosyltransferase activity IBA


Pathways (from Reactome)
Pathway description
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101266 P68400 / CSNK2A1 / casein kinase 2 alpha 1  / reaction
 ENSG00000111664 GNB3 / P16520 / G protein subunit beta 3  / complex
 ENSG00000114450 GNB4 / Q9HAV0 / G protein subunit beta 4  / complex
 ENSG00000172354 GNB2 / P62879 / G protein subunit beta 2  / complex
 ENSG00000078369 GNB1 / P62873 / G protein subunit beta 1  / complex
 ENSG00000186469 GNG2 / P59768 / G protein subunit gamma 2  / reaction / complex
 ENSG00000070770 P19784 / CSNK2A2 / casein kinase 2 alpha 2  / reaction
 ENSG00000069966 GNB5 / O14775 / G protein subunit beta 5  / complex
 ENSG00000204435 CSNK2B / P67870 / casein kinase 2 beta  / reaction






 

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