ENSG00000139725


Homo sapiens

Features
Gene ID: ENSG00000139725
  
Biological name :RHOF
  
Synonyms : Q9HBH0 / ras homolog family member F, filopodia associated / RHOF
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.31
Gene start: 121777754
Gene end: 121803403
  
Corresponding Affymetrix probe sets: 1554538_at (Human Genome U133 Plus 2.0 Array)   1554539_a_at (Human Genome U133 Plus 2.0 Array)   219045_at (Human Genome U133 Plus 2.0 Array)   222812_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476574
Ensembl peptide - ENSP00000440397
Ensembl peptide - ENSP00000476444
Ensembl peptide - ENSP00000267205
Ensembl peptide - ENSP00000477391
Ensembl peptide - ENSP00000476987
NCBI entrez gene - 54509     See in Manteia.
RefSeq - NM_019034
RefSeq Peptide - NP_061907
swissprot - V9GYQ1
swissprot - F5GXB1
swissprot - Q9HBH0
swissprot - V9GY67
swissprot - V9GYB3
Ensembl - ENSG00000139725
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhofENSDARG00000054389Danio rerio
 RHOFENSGALG00000039724Gallus gallus
 RhofENSMUSG00000029449Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RHOD / O00212 / ras homolog family member DENSG0000017315650
RHOC / P08134 / ras homolog family member CENSG0000015536645
RHOA / P61586 / ras homolog family member AENSG0000006756044
RHOB / P62745 / ras homolog family member BENSG0000014387843
RND3 / P61587 / Rho family GTPase 3ENSG0000011596341
RND2 / P52198 / Rho family GTPase 2ENSG0000010883038
RND1 / Q92730 / Rho family GTPase 1ENSG0000017260236
AL603832.3ENSG0000027181029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IDA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton NAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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