ENSG00000173156


Homo sapiens

Features
Gene ID: ENSG00000173156
  
Biological name :RHOD
  
Synonyms : O00212 / ras homolog family member D / RHOD
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.2
Gene start: 67056818
Gene end: 67072013
  
Corresponding Affymetrix probe sets: 209885_at (Human Genome U133 Plus 2.0 Array)   31846_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432003
Ensembl peptide - ENSP00000308576
NCBI entrez gene - 29984     See in Manteia.
OMIM - 605781
RefSeq - NM_001300886
RefSeq - NM_014578
RefSeq Peptide - NP_001287815
RefSeq Peptide - NP_055393
swissprot - O00212
swissprot - E9PIG5
Ensembl - ENSG00000173156
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RhodENSMUSG00000041845Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RHOF / Q9HBH0 / ras homolog family member F, filopodia associatedENSG0000013972550
RHOA / P61586 / ras homolog family member AENSG0000006756047
RHOC / P08134 / ras homolog family member CENSG0000015536646
RHOB / P62745 / ras homolog family member BENSG0000014387846
RND3 / P61587 / Rho family GTPase 3ENSG0000011596339
RND2 / P52198 / Rho family GTPase 2ENSG0000010883038
RND1 / Q92730 / Rho family GTPase 1ENSG0000017260236
AL603832.3ENSG0000027181030


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0007266 Rho protein signal transduction TAS
 biological_processGO:0030032 lamellipodium assembly IMP
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0045785 positive regulation of cell adhesion IMP
 biological_processGO:0048041 focal adhesion assembly IMP
 biological_processGO:0051017 actin filament bundle assembly IMP
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0051893 regulation of focal adhesion assembly IEA
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000147202 DIAPH2 / O60879 / diaphanous related formin 2  / reaction / complex
 ENSG00000197122 SRC / P12931 / SRC proto-oncogene, non-receptor tyrosine kinase  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr