ENSMUSG00000029449


Mus musculus

Features
Gene ID: ENSMUSG00000029449
  
Biological name :Rhof
  
Synonyms : Q8BYP3 / ras homolog family member F (in filopodia) / Rhof
  
Possible biological names infered from orthology : Q9HBH0 / ras homolog family member F, filopodia associated
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 123103044
Gene end: 123132692
  
Corresponding Affymetrix probe sets: 10533603 (MoGene1.0st)   1434794_at (Mouse Genome 430 2.0 Array)   1455902_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031401
Ensembl peptide - ENSMUSP00000124866
Ensembl peptide - ENSMUSP00000140177
NCBI entrez gene - 23912     See in Manteia.
MGI - MGI:1345629
RefSeq - NM_175092
RefSeq Peptide - NP_780301
swissprot - Q4VA10
swissprot - Q8BYP3
Ensembl - ENSMUSG00000029449
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhofENSDARG00000054389Danio rerio
 RHOFENSGALG00000039724Gallus gallus
 RHOFENSG00000139725Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rhod / P97348 / ras homolog family member D / O00212*ENSMUSG0000004184550
Rhoc / Q62159 / Rho-related GTP-binding protein RhoC / P08134* / ras homolog family member C*ENSMUSG0000000223344
Rhoa / Q9QUI0 / ras homolog family member A / P61586*ENSMUSG0000000781543
Rhob / P62746 / ras homolog family member B / P62745*ENSMUSG0000005436442
4930544G11Rik / RIKEN cDNA 4930544G11 geneENSMUSG0000003646342
Rnd3 / P61588 / Rho-related GTP-binding protein RhoE / P61587* / Rho family GTPase 3*ENSMUSG0000001714440
Rnd2 / Q9QYM5 / Rho family GTPase 2 / P52198*ENSMUSG0000000131338
Rnd1 / Q8BLR7 / Rho-related GTP-binding protein Rho6 / Q92730* / Rho family GTPase 1*ENSMUSG0000005485536


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003179 decreased platelet count "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]
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Allelic Composition: Phf2tm1.2Yima/Phf2tm1.2Yima,Ndor1Tg(UBC-cre/ERT2)1Ejb/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * C57BL/6J * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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