ENSMUSG00000054855


Mus musculus

Features
Gene ID: ENSMUSG00000054855
  
Biological name :Rnd1
  
Synonyms : Q8BLR7 / Rho-related GTP-binding protein Rho6 / Rnd1
  
Possible biological names infered from orthology : Q92730 / Rho family GTPase 1
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F1
Gene start: 98663421
Gene end: 98677461
  
Corresponding Affymetrix probe sets: 10432236 (MoGene1.0st)   1455197_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003451
Ensembl peptide - ENSMUSP00000104777
Ensembl peptide - ENSMUSP00000113830
NCBI entrez gene - 223881     See in Manteia.
MGI - MGI:2444878
RefSeq - NM_172612
RefSeq Peptide - NP_766200
swissprot - Q8BLR7
Ensembl - ENSMUSG00000054855
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnd1aENSDARG00000030547Danio rerio
 rnd1bENSDARG00000004218Danio rerio
 RND1ENSG00000172602Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rnd3 / P61588 / Rho-related GTP-binding protein RhoE / P61587* / Rho family GTPase 3*ENSMUSG0000001714462
Rnd2 / Q9QYM5 / Rho family GTPase 2 / P52198*ENSMUSG0000000131351
Rhoc / Q62159 / Rho-related GTP-binding protein RhoC / P08134* / ras homolog family member C*ENSMUSG0000000223336
Rhoa / Q9QUI0 / ras homolog family member A / P61586*ENSMUSG0000000781536
4930544G11Rik / RIKEN cDNA 4930544G11 geneENSMUSG0000003646336
Rhob / P62746 / ras homolog family member B / P62745*ENSMUSG0000005436434
Rhof / Q8BYP3 / ras homolog family member F (in filopodia) / Q9HBH0* / ras homolog family member F, filopodia associated*ENSMUSG0000002944933
Rhod / P97348 / ras homolog family member D / O00212*ENSMUSG0000004184531


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization ISO
 biological_processGO:0007162 negative regulation of cell adhesion ISO
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0016322 neuron remodeling ISO
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005912 adherens junction ISO
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Sema4D mediated inhibition of cell attachment and migration
Sema4D induced cell migration and growth-cone collapse


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000007815 Rhoa / Q9QUI0 / ras homolog family member A / P61586*  / reaction
 ENSMUSG00000059495 Q8R4H2 / Arhgef12 / Mus musculus Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12), transcript variant 2, mRNA. / Q9NZN5* / Rho guanine nucleotide exchange factor 12*  / reaction / complex
 ENSMUSG00000041977 Arhgef11 / Rho guanine nucleotide exchange factor (GEF) 11 / O15085* / Rho guanine nucleotide exchange factor 11*  / reaction / complex
 ENSMUSG00000038387 Rras / P10833 / related RAS viral (r-ras) oncogene / P10301* / RAS related*  / reaction
 ENSMUSG00000054364 Rhob / P62746 / ras homolog family member B / P62745*  / reaction
 ENSMUSG00000002233 Rhoc / Q62159 / Rho-related GTP-binding protein RhoC / P08134* / ras homolog family member C*  / reaction
 ENSMUSG00000021451 O09126 / Sema4d / Semaphorin-4D / Q92854*  / complex / reaction
 ENSMUSG00000025810 Nrp1 / P97333 / Neuropilin-1 / O14786*  / complex / reaction
 ENSMUSG00000028883 O08665 / Sema3a / Semaphorin-3A / Q14563*  / complex / reaction
 ENSMUSG00000030084 P70206 / Plxna1 / Plexin-A1 / Q9UIW2*  / reaction / complex
 ENSMUSG00000062312 Erbb2 / P70424 / Receptor tyrosine-protein kinase erbB-2 / P04626* / erb-b2 receptor tyrosine kinase 2*  / complex
 ENSMUSG00000053646 Plxnb1 / Q8CJH3 / plexin B1 / O43157*  / complex / reaction
 ENSMUSG00000009376 Met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / reaction / complex
 ENSMUSG00000001847 Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*  / reaction / complex
 ENSMUSG00000058230 Q91YM2 / Arhgap35 / Rho GTPase activating protein 35 / Q9NRY4*  / complex / reaction
 ENSMUSG00000053158 Fes / P16879 / Tyrosine-protein kinase Fes/Fps / P07332* / FES proto-oncogene, tyrosine kinase*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr