ENSDARG00000030547


Danio rerio

Features
Gene ID: ENSDARG00000030547
  
Biological name :rnd1a
  
Synonyms : Rho family GTPase 1a / rnd1a
  
Possible biological names infered from orthology : Q8BLR7 / Q92730 / Rho family GTPase 1 / Rho-related GTP-binding protein Rho6 / RND1
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 17800717
Gene end: 17815253
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000044985
Ensembl peptide - ENSDARP00000104531
NCBI entrez gene - 405780     See in Manteia.
RefSeq - NM_212854
RefSeq Peptide - NP_998019
swissprot - F6P903
swissprot - Q6TEM4
ZFIN ID - ZDB-GENE-040630-6
Ensembl - ENSDARG00000030547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RND1ENSG00000172602Homo sapiens
 Rnd1ENSMUSG00000054855Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rnd1b / Rho family GTPase 1b / RND1* / Q92730* / Q8BLR7* / Rho family GTPase 1* / Rho-related GTP-binding protein Rho6 *ENSDARG0000000421884
rnd3a / Rho family GTPase 3a / RND3* / P61588* / P61587* / Rho family GTPase 3* / Rho-related GTP-binding protein RhoE *ENSDARG0000007679960
rnd2 / Rho family GTPase 2 / P52198* / Q9QYM5*ENSDARG0000007073553
rnd3b / Rho family GTPase 3b / RND3* / P61588* / P61587* / Rho family GTPase 3* / Rho-related GTP-binding protein RhoE *ENSDARG0000000739653
rhoca / ras homolog family member Ca / RHOC* / Q62159* / P08134* / ras homolog family member C* / Rho-related GTP-binding protein RhoC *ENSDARG0000002130938
rhoac / Q7T2E8 / ras homolog gene family, member AcENSDARG0000011605838
rhoaa / Q6NUX8 / ras homolog gene family, member AaENSDARG0000002684538
rhoab / Q6DHM9 / ras homolog gene family, member Ab / RHOA* / Q9QUI0* / P61586* / ras homolog family member A*ENSDARG0000009467338
rhocb / Q6DHE8 / ras homolog family member Cb / RHOC* / Q62159* / P08134* / ras homolog family member C* / Rho-related GTP-binding protein RhoC *ENSDARG0000001832837
rhof / ras homolog family member F / Q9HBH0* / Q8BYP3* / ras homolog family member F (in filopodia)* / ras homolog family member F, filopodia associated*ENSDARG0000005438931


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Sema4D mediated inhibition of cell attachment and migration
Sema4D induced cell migration and growth-cone collapse


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026294 erbb2 / erb-b2 receptor tyrosine kinase 2 / P04626* / P70424* / Receptor tyrosine-protein kinase erbB-2 *  / complex
 ENSDARG00000094673 rhoab / Q6DHM9 / ras homolog gene family, member Ab / RHOA* / Q9QUI0* / P61586* / ras homolog family member A*  / reaction
 ENSDARG00000018328 rhocb / Q6DHE8 / ras homolog family member Cb / RHOC* / Q62159* / P08134* / ras homolog family member C* / Rho-related GTP-binding protein RhoC *  / reaction
 ENSDARG00000021309 rhoca / ras homolog family member Ca / RHOC* / Q62159* / P08134* / ras homolog family member C* / Rho-related GTP-binding protein RhoC *  / reaction
 ENSDARG00000030532 arhgef12a / Rho guanine nucleotide exchange factor (GEF) 12a / Q9NZN5* / ARHGEF12* / Rho guanine nucleotide exchange factor 12*  / reaction / complex
 ENSDARG00000062577 arhgap35a / Rho GTPase activating protein 35a / Q91YM2* / Q9NRY4* / ARHGAP35* / Rho GTPase activating protein 35*  / complex / reaction
 ENSDARG00000060297 arhgap35b / Rho GTPase activating protein 35b / Q91YM2* / Q9NRY4* / ARHGAP35* / Rho GTPase activating protein 35*  / complex / reaction
 ENSDARG00000070903 met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / reaction / complex
 ENSDARG00000100913 arhgef12b / Rho guanine nucleotide exchange factor (GEF) 12b / Q8R4H2* / Q9NZN5* / ARHGEF12* / Rho guanine nucleotide exchange factor 12* / Mus musculus Rho guanine nucleotide exchange fact...  / complex / reaction






 

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