ENSG00000156711


Homo sapiens

Features
Gene ID: ENSG00000156711
  
Biological name :MAPK13
  
Synonyms : MAPK13 / mitogen-activated protein kinase 13 / O15264
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.31
Gene start: 36127809
Gene end: 36144524
  
Corresponding Affymetrix probe sets: 210058_at (Human Genome U133 Plus 2.0 Array)   210059_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000211287
Ensembl peptide - ENSP00000362871
Ensembl peptide - ENSP00000362864
NCBI entrez gene - 5603     See in Manteia.
OMIM - 602899
RefSeq - NM_002754
RefSeq Peptide - NP_002745
swissprot - A0A024RD04
swissprot - O15264
swissprot - Q5R3E6
Ensembl - ENSG00000156711
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BX324164.5ENSDARG00000110143Danio rerio
 MAPK13ENSGALG00000030966Gallus gallus
 Mapk13ENSMUSG00000004864Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAPK12 / P53778 / mitogen-activated protein kinase 12ENSG0000018813065
MAPK14 / Q16539 / mitogen-activated protein kinase 14ENSG0000011206259
MAPK11 / Q15759 / mitogen-activated protein kinase 11ENSG0000018538658
MAPK10 / P53779 / mitogen-activated protein kinase 10ENSG0000010933947
MAPK8 / P45983 / mitogen-activated protein kinase 8ENSG0000010764346
MAPK9 / P45984 / mitogen-activated protein kinase 9ENSG0000005074846


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003527  Mitogen-activated protein (MAP) kinase, conserved site
 IPR008352  Mitogen-activated protein (MAP) kinase p38-like
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006970 response to osmotic stress IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0032755 positive regulation of interleukin-6 production IMP
 biological_processGO:0034644 cellular response to UV IDA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0050729 positive regulation of inflammatory response IC
 biological_processGO:0051403 stress-activated MAPK cascade IDA
 biological_processGO:0070301 cellular response to hydrogen peroxide IDA
 biological_processGO:0071347 cellular response to interleukin-1 IDA
 biological_processGO:0072709 cellular response to sorbitol IDA
 biological_processGO:0072740 cellular response to anisomycin IDA
 biological_processGO:1903936 cellular response to sodium arsenite IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0004707 MAP kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
NOD1/2 Signaling Pathway
p38MAPK events
DSCAM interactions
VEGFA-VEGFR2 Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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