ENSG00000162482


Homo sapiens

Features
Gene ID: ENSG00000162482
  
Biological name :AKR7A3
  
Synonyms : AKR7A3 / aldo-keto reductase family 7 member A3 / O95154
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.13
Gene start: 19282558
Gene end: 19289250
  
Corresponding Affymetrix probe sets: 206469_x_at (Human Genome U133 Plus 2.0 Array)   216381_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355377
NCBI entrez gene - 22977     See in Manteia.
OMIM - 608477
RefSeq - NM_012067
RefSeq - XM_011541046
RefSeq Peptide - NP_036199
swissprot - O95154
Ensembl - ENSG00000162482
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akr7a3ENSDARG00000016649Danio rerio
 ENSGALG00000004005Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AKR7L / Q8NHP1 / aldo-keto reductase family 7 like (gene/pseudogene)ENSG0000021145492
AKR7A2 / O43488 / aldo-keto reductase family 7 member A2ENSG0000005337188
KCNAB1 / Q14722 / potassium voltage-gated channel subfamily A member regulatory beta subunit 1ENSG0000016928226
KCNAB2 / Q13303 / potassium voltage-gated channel subfamily A regulatory beta subunit 2ENSG0000006942426
KCNAB3 / O43448 / potassium voltage-gated channel subfamily A regulatory beta subunit 3ENSG0000017004926


Protein motifs (from Interpro)
Interpro ID Name
 IPR023210  NADP-dependent oxidoreductase domain
 IPR036812  NADP-dependent oxidoreductase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006081 cellular aldehyde metabolic process TAS
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004033 aldo-keto reductase (NADP) activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0009055 electron transfer activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Aflatoxin activation and detoxification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000162482 AKR7A3 / O95154 / aldo-keto reductase family 7 member A3  / complex






 

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