ENSG00000211454


Homo sapiens

Features
Gene ID: ENSG00000211454
  
Biological name :AKR7L
  
Synonyms : AKR7L / aldo-keto reductase family 7 like (gene/pseudogene) / Q8NHP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.13
Gene start: 19265982
Gene end: 19274194
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000402491
Ensembl peptide - ENSP00000406430
Ensembl peptide - ENSP00000411913
swissprot - Q8NHP1
Ensembl - ENSG00000211454
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akr7a3ENSDARG00000016649Danio rerio
 ENSGALG00000004005Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AKR7A3 / O95154 / aldo-keto reductase family 7 member A3ENSG0000016248292
AKR7A2 / O43488 / aldo-keto reductase family 7 member A2ENSG0000005337190
KCNAB1 / Q14722 / potassium voltage-gated channel subfamily A member regulatory beta subunit 1ENSG0000016928226
KCNAB3 / O43448 / potassium voltage-gated channel subfamily A regulatory beta subunit 3ENSG0000017004926
KCNAB2 / Q13303 / potassium voltage-gated channel subfamily A regulatory beta subunit 2ENSG0000006942425


Protein motifs (from Interpro)
Interpro ID Name
 IPR023210  NADP-dependent oxidoreductase domain
 IPR036812  NADP-dependent oxidoreductase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004033 aldo-keto reductase (NADP) activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Aflatoxin activation and detoxification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000211454 AKR7L / Q8NHP1 / aldo-keto reductase family 7 like (gene/pseudogene)  / complex






 

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