ENSG00000170049


Homo sapiens

Features
Gene ID: ENSG00000170049
  
Biological name :KCNAB3
  
Synonyms : KCNAB3 / O43448 / potassium voltage-gated channel subfamily A regulatory beta subunit 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 7921859
Gene end: 7929803
  
Corresponding Affymetrix probe sets: 221413_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302719
Ensembl peptide - ENSP00000458237
Ensembl peptide - ENSP00000461290
NCBI entrez gene - 9196     See in Manteia.
OMIM - 604111
RefSeq - XM_017025306
RefSeq - NM_004732
RefSeq - XM_011524068
RefSeq - XM_017025304
RefSeq - XM_017025305
RefSeq Peptide - NP_004723
swissprot - I3L4I8
swissprot - I3L0P1
swissprot - O43448
Ensembl - ENSG00000170049
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01083937.1ENSDARG00000074320Danio rerio
 Kcnab3ENSMUSG00000018470Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNAB1 / Q14722 / potassium voltage-gated channel subfamily A member regulatory beta subunit 1ENSG0000016928265
KCNAB2 / Q13303 / potassium voltage-gated channel subfamily A regulatory beta subunit 2ENSG0000006942462
AKR7A3 / O95154 / aldo-keto reductase family 7 member A3ENSG0000016248222
AKR7L / Q8NHP1 / aldo-keto reductase family 7 like (gene/pseudogene)ENSG0000021145422
AKR7A2 / O43488 / aldo-keto reductase family 7 member A2ENSG0000005337121


Protein motifs (from Interpro)
Interpro ID Name
 IPR005399  Potassium channel, voltage-dependent, beta subunit, KCNAB-related
 IPR005402  Potassium channel, voltage-dependent, beta subunit, KCNAB3
 IPR005983  Potassium channel, voltage-dependent, beta subunit, KCNAB
 IPR023210  NADP-dependent oxidoreductase domain
 IPR036812  NADP-dependent oxidoreductase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0015459 potassium channel regulator activity TAS


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069424 KCNAB2 / Q13303 / potassium voltage-gated channel subfamily A regulatory beta subunit 2  / complex
 ENSG00000169282 KCNAB1 / Q14722 / potassium voltage-gated channel subfamily A member regulatory beta subunit 1  / complex
 ENSG00000170049 KCNAB3 / O43448 / potassium voltage-gated channel subfamily A regulatory beta subunit 3  / complex






 

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