ENSG00000162639


Homo sapiens

Features
Gene ID: ENSG00000162639
  
Biological name :HENMT1
  
Synonyms : HEN methyltransferase 1 / HENMT1 / Q5T8I9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.3
Gene start: 108648290
Gene end: 108661526
  
Corresponding Affymetrix probe sets: 225841_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000403953
Ensembl peptide - ENSP00000359048
Ensembl peptide - ENSP00000359049
Ensembl peptide - ENSP00000385655
NCBI entrez gene - 113802     See in Manteia.
OMIM - 612178
RefSeq - XM_017000179
RefSeq - NM_001102592
RefSeq - NM_144584
RefSeq - XM_005270411
RefSeq Peptide - NP_653185
RefSeq Peptide - NP_001096062
swissprot - Q5T8I9
swissprot - X6RGV9
swissprot - A0A0A0MRN1
Ensembl - ENSG00000162639
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 henmt1ENSDARG00000018871Danio rerio
 E1BVR9ENSGALG00000001959Gallus gallus
 Henmt1ENSMUSG00000045662Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026610  3"-RNA ribose 2"-O-methyltransferase, Hen1
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001510 RNA methylation ISS
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034587 piRNA metabolic process ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043186 P granule ISS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008171 O-methyltransferase activity ISS
 molecular_functionGO:0008173 RNA methyltransferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PIWI-interacting RNA (piRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125207 PIWIL1 / Q96J94 / piwi like RNA-mediated gene silencing 1  / reaction
 ENSG00000143194 MAEL / Q96JY0 / maelstrom spermatogenic transposon silencer  / reaction
 ENSG00000156414 TDRD9 / Q8NDG6 / tudor domain containing 9  / reaction
 ENSG00000134627 PIWIL4 / Q7Z3Z4 / piwi like RNA-mediated gene silencing 4  / reaction
 ENSG00000180113 TDRD6 / O60522 / tudor domain containing 6  / reaction
 ENSG00000182134 TDRKH / Q9Y2W6 / tudor and KH domain containing  / reaction






 

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