ENSG00000182134


Homo sapiens

Features
Gene ID: ENSG00000182134
  
Biological name :TDRKH
  
Synonyms : Q9Y2W6 / TDRKH / tudor and KH domain containing
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 151770107
Gene end: 151791416
  
Corresponding Affymetrix probe sets: 221052_at (Human Genome U133 Plus 2.0 Array)   221053_s_at (Human Genome U133 Plus 2.0 Array)   223530_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431557
Ensembl peptide - ENSP00000416645
Ensembl peptide - ENSP00000432452
Ensembl peptide - ENSP00000437147
Ensembl peptide - ENSP00000433678
Ensembl peptide - ENSP00000357812
Ensembl peptide - ENSP00000357813
Ensembl peptide - ENSP00000357815
Ensembl peptide - ENSP00000357817
Ensembl peptide - ENSP00000357819
Ensembl peptide - ENSP00000395718
NCBI entrez gene - 11022     See in Manteia.
OMIM - 609501
RefSeq - XM_017000130
RefSeq - NM_006862
RefSeq - XM_005244856
RefSeq - XM_017000122
RefSeq - XM_017000123
RefSeq - XM_017000124
RefSeq - XM_017000125
RefSeq - XM_017000126
RefSeq - XM_017000127
RefSeq - XM_017000128
RefSeq - XM_017000129
RefSeq - NM_001083963
RefSeq - NM_001083964
RefSeq - NM_001083965
RefSeq Peptide - NP_006853
RefSeq Peptide - NP_001077432
RefSeq Peptide - NP_001077433
RefSeq Peptide - NP_001077434
swissprot - E9PQX4
swissprot - B7ZAG4
swissprot - Q9Y2W6
swissprot - E9PKN8
swissprot - F6TB26
swissprot - Q5SZR4
Ensembl - ENSG00000182134
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tdrkhENSDARG00000053474Danio rerio
 TDRKHENSGALG00000031812Gallus gallus
 TdrkhENSMUSG00000041912Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TDRD5 / Q8NAT2 / tudor domain containing 5ENSG0000016278223
TDRD6 / O60522 / tudor domain containing 6ENSG0000018011315
B5MCY1 / TDRD15 / tudor domain containing 15ENSG0000021881915
TDRD1 / Q9BXT4 / tudor domain containing 1ENSG0000009562714
RNF17 / Q9BXT8 / ring finger protein 17ENSG0000013297212


Protein motifs (from Interpro)
Interpro ID Name
 IPR002999  Tudor domain
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR015946  K homology domain-like, alpha/beta
 IPR035437  SNase-like, OB-fold superfamily
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007140 male meiotic nuclear division ISS
 biological_processGO:0007283 spermatogenesis ISS
 biological_processGO:0009566 fertilization ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0034587 piRNA metabolic process ISS
 biological_processGO:0043046 DNA methylation involved in gamete generation ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0071546 pi-body ISS
 cellular_componentGO:0071547 piP-body ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
PIWI-interacting RNA (piRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125207 PIWIL1 / Q96J94 / piwi like RNA-mediated gene silencing 1  / complex
 ENSG00000134627 PIWIL4 / Q7Z3Z4 / piwi like RNA-mediated gene silencing 4  / complex
 ENSG00000156414 TDRD9 / Q8NDG6 / tudor domain containing 9  / complex
 ENSG00000180113 TDRD6 / O60522 / tudor domain containing 6  / complex
 ENSG00000143194 MAEL / Q96JY0 / maelstrom spermatogenic transposon silencer  / complex
 ENSG00000162639 HENMT1 / Q5T8I9 / HEN methyltransferase 1  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr