ENSG00000163312


Homo sapiens

Features
Gene ID: ENSG00000163312
  
Biological name :HELQ
  
Synonyms : helicase, POLQ like / HELQ / Q8TDG4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.23
Gene start: 83407343
Gene end: 83455856
  
Corresponding Affymetrix probe sets: 1554341_a_at (Human Genome U133 Plus 2.0 Array)   1554342_s_at (Human Genome U133 Plus 2.0 Array)   228736_at (Human Genome U133 Plus 2.0 Array)   241784_x_at (Human Genome U133 Plus 2.0 Array)   243809_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424186
Ensembl peptide - ENSP00000424539
Ensembl peptide - ENSP00000295488
NCBI entrez gene - 113510     See in Manteia.
OMIM - 606769
RefSeq - XM_017007683
RefSeq - NM_133636
RefSeq - XM_005262711
RefSeq - XM_005262713
RefSeq - XM_006714076
RefSeq - XM_017007679
RefSeq - XM_017007680
RefSeq - XM_017007682
RefSeq - NM_001297755
RefSeq - NM_001297756
RefSeq - NM_001297757
RefSeq Peptide - NP_598375
RefSeq Peptide - NP_001284684
RefSeq Peptide - NP_001284685
RefSeq Peptide - NP_001284686
swissprot - Q8TDG4
swissprot - E3W982
swissprot - E3W980
Ensembl - ENSG00000163312
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 helqENSDARG00000079818Danio rerio
 ENSGALG00000043261Gallus gallus
 ENSGALG00000011208Gallus gallus
 HelqENSMUSG00000035266Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
POLQ / O75417 / DNA polymerase thetaENSG0000005134126
O75643 / SNRNP200 / small nuclear ribonucleoprotein U5 subunit 200ENSG0000014402817
ASCC3 / Q8N3C0 / activating signal cointegrator 1 complex subunit 3ENSG0000011224916
POLN / Q7Z5Q5 / DNA polymerase nuENSG000001309975


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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