ENSG00000163520


Homo sapiens

Features
Gene ID: ENSG00000163520
  
Biological name :FBLN2
  
Synonyms : FBLN2 / fibulin 2 / P98095
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.1
Gene start: 13549131
Gene end: 13638422
  
Corresponding Affymetrix probe sets: 203886_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420042
Ensembl peptide - ENSP00000399224
Ensembl peptide - ENSP00000420164
Ensembl peptide - ENSP00000295760
Ensembl peptide - ENSP00000295761
Ensembl peptide - ENSP00000384169
NCBI entrez gene - 2199     See in Manteia.
OMIM - 135821
RefSeq - XM_006713026
RefSeq - NM_001004019
RefSeq - NM_001165035
RefSeq - NM_001998
RefSeq Peptide - NP_001158507
RefSeq Peptide - NP_001004019
RefSeq Peptide - NP_001989
swissprot - P98095
swissprot - H7BXL0
swissprot - C9JQS6
swissprot - H7C1A3
Ensembl - ENSG00000163520
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbln2ENSDARG00000015156Danio rerio
 Fbln2ENSMUSG00000064080Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBN3 / Q75N90 / fibrillin 3ENSG0000014244926
FBN1 / P35555 / fibrillin 1ENSG0000016614726
FBN2 / P35556 / fibrillin 2ENSG0000013882926
FBLN1 / P23142 / fibulin 1ENSG0000007794225
LTBP2 / Q14767 / latent transforming growth factor beta binding protein 2ENSG0000011968123
LTBP1 / Q14766 / latent transforming growth factor beta binding protein 1ENSG0000004932322
LTBP4 / Q8N2S1 / latent transforming growth factor beta binding protein 4ENSG0000009000621
LTBP3 / Q9NS15 / latent transforming growth factor beta binding protein 3ENSG0000016805619
EFEMP2 / O95967 / EGF containing fibulin extracellular matrix protein 2ENSG0000017263813
FBLN5 / Q9UBX5 / fibulin 5ENSG0000014009212
EFEMP1 / Q12805 / EGF containing fibulin extracellular matrix protein 1ENSG0000011538012


Protein motifs (from Interpro)
Interpro ID Name
 IPR000020  Anaphylatoxin/fibulin
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain
 IPR037286  Fibulin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1903561 extracellular vesicle HDA
 molecular_functionGO:0005201 extracellular matrix structural constituent TAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0050840 extracellular matrix binding IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115414 FN1 / P02751 / fibronectin 1  / complex / reaction






 

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