ENSG00000163545


Homo sapiens

Features
Gene ID: ENSG00000163545
  
Biological name :NUAK2
  
Synonyms : NUAK2 / NUAK family kinase 2 / Q9H093
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 205302059
Gene end: 205321791
  
Corresponding Affymetrix probe sets: 220987_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356125
NCBI entrez gene - 81788     See in Manteia.
OMIM - 608131
RefSeq - NM_030952
RefSeq Peptide - NP_112214
swissprot - B4E0Y5
swissprot - Q9H093
Ensembl - ENSG00000163545
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nuak2ENSDARG00000063661Danio rerio
 NUAK2ENSGALG00000036616Gallus gallus
 Nuak2ENSMUSG00000009772Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NUAK1 / O60285 / NUAK family kinase 1ENSG0000007459054
P54646 / PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2ENSG0000016240925
PRKAA1 / Q13131 / protein kinase AMP-activated catalytic subunit alpha 1ENSG0000013235625
TRIB1 / Q96RU8 / tribbles pseudokinase 1ENSG0000017333414
TRIB2 / Q92519 / tribbles pseudokinase 2ENSG0000007157513
TRIB3 / Q96RU7 / tribbles pseudokinase 3ENSG0000010125513
STK40 / Q8N2I9 / serine/threonine kinase 40ENSG0000019618212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030036 actin cytoskeleton organization IDA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0042149 cellular response to glucose starvation IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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