ENSG00000196182


Homo sapiens

Features
Gene ID: ENSG00000196182
  
Biological name :STK40
  
Synonyms : Q8N2I9 / serine/threonine kinase 40 / STK40
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.3
Gene start: 36339624
Gene end: 36385896
  
Corresponding Affymetrix probe sets: 223852_s_at (Human Genome U133 Plus 2.0 Array)   225015_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352245
Ensembl peptide - ENSP00000362221
Ensembl peptide - ENSP00000362222
Ensembl peptide - ENSP00000362224
NCBI entrez gene - 83931     See in Manteia.
OMIM - 609437
RefSeq - NM_001282546
RefSeq - NM_001282547
RefSeq - NM_032017
RefSeq Peptide - NP_001269475
RefSeq Peptide - NP_001269476
RefSeq Peptide - NP_114406
swissprot - Q8N2I9
Ensembl - ENSG00000196182
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk40ENSDARG00000098135Danio rerio
 STK40ENSGALG00000032925Gallus gallus
 Stk40ENSMUSG00000042608Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRIB3 / Q96RU7 / tribbles pseudokinase 3ENSG0000010125522
TRIB1 / Q96RU8 / tribbles pseudokinase 1ENSG0000017333420
TRIB2 / Q92519 / tribbles pseudokinase 2ENSG0000007157518
NUAK2 / Q9H093 / NUAK family kinase 2ENSG0000016354518
NUAK1 / O60285 / NUAK family kinase 1ENSG0000007459018
P54646 / PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2ENSG0000016240916
PRKAA1 / Q13131 / protein kinase AMP-activated catalytic subunit alpha 1ENSG0000013235616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR024104  Pseudokinase tribbles family/serine-threonine-protein kinase 40
 IPR024236  Serine/threonine-protein kinase 40


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003016 respiratory system process IEA
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043408 regulation of MAPK cascade IEA
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0060425 lung morphogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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