ENSG00000163810


Homo sapiens

Features
Gene ID: ENSG00000163810
  
Biological name :TGM4
  
Synonyms : P49221 / TGM4 / transglutaminase 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p21.31
Gene start: 44874608
Gene end: 44914990
  
Corresponding Affymetrix probe sets: 206260_at (Human Genome U133 Plus 2.0 Array)   217566_s_at (Human Genome U133 Plus 2.0 Array)   217567_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296125
Ensembl peptide - ENSP00000403711
NCBI entrez gene - 7047     See in Manteia.
OMIM - 600585
RefSeq - XM_011534042
RefSeq - NM_003241
RefSeq Peptide - NP_003232
swissprot - P49221
swissprot - F8WCU8
Ensembl - ENSG00000163810
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TGM4ENSGALG00000033171Gallus gallus
 Tgm4ENSMUSG00000025787Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TGM1 / P22735 / transglutaminase 1ENSG0000009229537
TGM7 / Q96PF1 / transglutaminase 7ENSG0000015949536
TGM6 / O95932 / transglutaminase 6ENSG0000016694835
TGM3 / Q08188 / transglutaminase 3ENSG0000012578034
TGM5 / O43548 / transglutaminase 5ENSG0000010405533
TGM2 / P21980 / transglutaminase 2ENSG0000019895932
F13A1 / P00488 / coagulation factor XIII A chainENSG0000012449131
EPB42 / P16452 / erythrocyte membrane protein band 4.2ENSG0000016694728


Protein motifs (from Interpro)
Interpro ID Name
 IPR001102  Transglutaminase, N-terminal
 IPR002931  Transglutaminase-like
 IPR008958  Transglutaminase, C-terminal
 IPR013783  Immunoglobulin-like fold
 IPR013808  Transglutaminase, active site
 IPR014756  Immunoglobulin E-set
 IPR023608  Protein-glutamine gamma-glutamyltransferase, animal
 IPR036238  Transglutaminase, C-terminal domain superfamily
 IPR036985  Transglutaminase-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018149 peptide cross-linking IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003810 protein-glutamine gamma-glutamyltransferase activity NAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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