ENSG00000165215


Homo sapiens

Features
Gene ID: ENSG00000165215
  
Biological name :CLDN3
  
Synonyms : claudin 3 / CLDN3 / O15551
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q11.23
Gene start: 73768997
Gene end: 73770270
  
Corresponding Affymetrix probe sets: 203953_s_at (Human Genome U133 Plus 2.0 Array)   203954_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378577
NCBI entrez gene - 1365     See in Manteia.
OMIM - 602910
RefSeq - NM_001306
RefSeq Peptide - NP_001297
swissprot - O15551
swissprot - Q75L79
Ensembl - ENSG00000165215
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CLDN3ENSGALG00000022557Gallus gallus
 Cldn3ENSMUSG00000070473Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLDN4 / O14493 / claudin 4ENSG0000018914368
CLDN9 / O95484 / claudin 9ENSG0000021393764
CLDN6 / P56747 / claudin 6ENSG0000018469759
CLDN5 / O00501 / claudin 5ENSG0000018411353
CLDN1 / O95832 / claudin 1ENSG0000016334749
CLDN8 / P56748 / claudin 8ENSG0000015628445
CLDN14 / O95500 / claudin 14ENSG0000015926144
CLDN7 / O95471 / claudin 7ENSG0000018188544
CLDN19 / Q8N6F1 / claudin 19ENSG0000016400743
CLDN2 / P57739 / claudin 2ENSG0000016537636


Protein motifs (from Interpro)
Interpro ID Name
 IPR003549  Claudin-3
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR006187  Claudin
 IPR017974  Claudin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEP
 biological_processGO:0003382 epithelial cell morphogenesis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0051260 protein homooligomerization IMP
 biological_processGO:0051291 protein heterooligomerization IGI
 biological_processGO:0070830 bicellular tight junction assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005923 bicellular tight junction ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0016327 apicolateral plasma membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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