ENSG00000156284


Homo sapiens

Features
Gene ID: ENSG00000156284
  
Biological name :CLDN8
  
Synonyms : claudin 8 / CLDN8 / P56748
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q22.11
Gene start: 30214006
Gene end: 30216073
  
Corresponding Affymetrix probe sets: 214598_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000382783
NCBI entrez gene - 9073     See in Manteia.
OMIM - 611231
RefSeq - NM_199328
RefSeq Peptide - NP_955360
swissprot - A0A0K0K1I9
swissprot - P56748
Ensembl - ENSG00000156284
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cldn17ENSDARG00000099950Danio rerio
 zgc:110333ENSDARG00000040628Danio rerio
 ENSGALG00000015841Gallus gallus
 ENSGALG00000044073Gallus gallus
 Cldn8ENSMUSG00000050520Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLDN9 / O95484 / claudin 9ENSG0000021393746
CLDN6 / P56747 / claudin 6ENSG0000018469744
CLDN3 / O15551 / claudin 3ENSG0000016521544
CLDN5 / O00501 / claudin 5ENSG0000018411340
CLDN7 / O95471 / claudin 7ENSG0000018188540
CLDN4 / O14493 / claudin 4ENSG0000018914340
CLDN1 / O95832 / claudin 1ENSG0000016334735
CLDN14 / O95500 / claudin 14ENSG0000015926135
CLDN19 / Q8N6F1 / claudin 19ENSG0000016400733
CLDN2 / P57739 / claudin 2ENSG0000016537632


Protein motifs (from Interpro)
Interpro ID Name
 IPR003926  Claudin-8
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR006187  Claudin
 IPR017974  Claudin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules ISS
 cellular_componentGO:0005783 endoplasmic reticulum HDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016327 apicolateral plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding ISS


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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