ENSG00000181885


Homo sapiens

Features
Gene ID: ENSG00000181885
  
Biological name :CLDN7
  
Synonyms : claudin 7 / CLDN7 / O95471
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 7259903
Gene end: 7263983
  
Corresponding Affymetrix probe sets: 202790_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467220
Ensembl peptide - ENSP00000353475
Ensembl peptide - ENSP00000460550
Ensembl peptide - ENSP00000445131
Ensembl peptide - ENSP00000396638
Ensembl peptide - ENSP00000460796
Ensembl peptide - ENSP00000465963
NCBI entrez gene - 1366     See in Manteia.
OMIM - 609131
RefSeq - NM_001185022
RefSeq - NM_001307
RefSeq - NM_001185023
RefSeq Peptide - NP_001171952
RefSeq Peptide - NP_001171951
RefSeq Peptide - NP_001298
swissprot - O95471
swissprot - F5H496
swissprot - I3L3L6
swissprot - I3L3X1
swissprot - K7EL87
swissprot - K7EP40
Ensembl - ENSG00000181885
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cldn7aENSDARG00000036376Danio rerio
 cldn7bENSDARG00000014047Danio rerio
 Cldn7ENSMUSG00000018569Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLDN1 / O95832 / claudin 1ENSG0000016334761
CLDN19 / Q8N6F1 / claudin 19ENSG0000016400753
CLDN3 / O15551 / claudin 3ENSG0000016521545
CLDN9 / O95484 / claudin 9ENSG0000021393745
CLDN14 / O95500 / claudin 14ENSG0000015926145
CLDN6 / P56747 / claudin 6ENSG0000018469744
CLDN5 / O00501 / claudin 5ENSG0000018411343
CLDN4 / O14493 / claudin 4ENSG0000018914343
CLDN8 / P56748 / claudin 8ENSG0000015628442
CLDN2 / P57739 / claudin 2ENSG0000016537637


Protein motifs (from Interpro)
Interpro ID Name
 IPR003552  Claudin-7
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR006187  Claudin
 IPR017974  Claudin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007162 negative regulation of cell adhesion IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules ISS
 biological_processGO:0032463 negative regulation of protein homooligomerization IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:2000147 positive regulation of cell motility IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016327 apicolateral plasma membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding ISS
 molecular_functionGO:0050839 cell adhesion molecule binding IEA


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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