ENSG00000165376


Homo sapiens

Features
Gene ID: ENSG00000165376
  
Biological name :CLDN2
  
Synonyms : claudin 2 / CLDN2 / P57739
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q22.3
Gene start: 106900164
Gene end: 106930861
  
Corresponding Affymetrix probe sets: 223509_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000336571
Ensembl peptide - ENSP00000441283
Ensembl peptide - ENSP00000443230
NCBI entrez gene - 9075     See in Manteia.
OMIM - 300520
RefSeq - NM_001171095
RefSeq - NM_001171092
RefSeq - NM_020384
RefSeq Peptide - NP_001164563
RefSeq Peptide - NP_001164566
RefSeq Peptide - NP_065117
swissprot - P57739
Ensembl - ENSG00000165376
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cldn2ENSDARG00000044387Danio rerio
 CLDN2ENSGALG00000007311Gallus gallus
 Cldn2ENSMUSG00000047230Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLDN14 / O95500 / claudin 14ENSG0000015926147
CLDN9 / O95484 / claudin 9ENSG0000021393737
CLDN19 / Q8N6F1 / claudin 19ENSG0000016400737
CLDN4 / O14493 / claudin 4ENSG0000018914336
CLDN6 / P56747 / claudin 6ENSG0000018469736
CLDN3 / O15551 / claudin 3ENSG0000016521535
CLDN1 / O95832 / claudin 1ENSG0000016334735
CLDN7 / O95471 / claudin 7ENSG0000018188534
CLDN5 / O00501 / claudin 5ENSG0000018411332
CLDN8 / P56748 / claudin 8ENSG0000015628432


Protein motifs (from Interpro)
Interpro ID Name
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR005411  Claudin-2
 IPR006187  Claudin
 IPR017974  Claudin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding ISS


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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