ENSG00000168140


Homo sapiens

Features
Gene ID: ENSG00000168140
  
Biological name :VASN
  
Synonyms : Q6EMK4 / VASN / vasorin
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 4371848
Gene end: 4383528
  
Corresponding Affymetrix probe sets: 225867_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000306864
NCBI entrez gene - 114990     See in Manteia.
OMIM - 608843
RefSeq - NM_138440
RefSeq Peptide - NP_612449
swissprot - Q6EMK4
Ensembl - ENSG00000168140
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vasnaENSDARG00000099266Danio rerio
 vasnbENSDARG00000102565Danio rerio
 VasnENSMUSG00000039646Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRIG1 / Q96JA1 / leucine rich repeats and immunoglobulin like domains 1ENSG0000014474923
LRIG2 / O94898 / leucine rich repeats and immunoglobulin like domains 2ENSG0000019879921
LRIG3 / Q6UXM1 / leucine rich repeats and immunoglobulin like domains 3ENSG0000013926320
ADGRA2 / Q96PE1 / adhesion G protein-coupled receptor A2ENSG0000002018118
ADGRA3 / Q8IWK6 / adhesion G protein-coupled receptor A3ENSG0000015299016
LGI1 / O95970 / leucine rich glioma inactivated 1ENSG0000010823112
LGI2 / Q8N0V4 / leucine rich repeat LGI family member 2ENSG0000015301211
LGI3 / Q8N145 / leucine rich repeat LGI family member 3ENSG0000016848111
LGI4 / Q8N135 / leucine rich repeat LGI family member 4ENSG0000015390211
ADGRA1 / Q86SQ6 / adhesion G protein-coupled receptor A1ENSG000001971775


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR000742  EGF-like domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003961  Fibronectin type III
 IPR013032  EGF-like, conserved site
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010719 negative regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0071461 cellular response to redox state IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0050431 transforming growth factor beta binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr