ENSG00000169231


Homo sapiens

Features
Gene ID: ENSG00000169231
  
Biological name :THBS3
  
Synonyms : P49746 / THBS3 / thrombospondin 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q22
Gene start: 155195588
Gene end: 155209051
  
Corresponding Affymetrix probe sets: 209561_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357362
Ensembl peptide - ENSP00000404040
Ensembl peptide - ENSP00000437353
Ensembl peptide - ENSP00000444792
Ensembl peptide - ENSP00000392207
NCBI entrez gene - 7059     See in Manteia.
OMIM - 188062
RefSeq - XM_017002206
RefSeq - XM_011509930
RefSeq - XM_011509931
RefSeq - XM_011509932
RefSeq - XM_011509933
RefSeq - XM_011509934
RefSeq - XM_011509935
RefSeq - XM_011509936
RefSeq - NM_001252607
RefSeq - NM_001252608
RefSeq - NM_007112
RefSeq - XM_006711498
RefSeq - XM_011509926
RefSeq - XM_011509927
RefSeq - XM_011509928
RefSeq - XM_011509929
RefSeq Peptide - NP_001239536
RefSeq Peptide - NP_001239537
RefSeq Peptide - NP_009043
swissprot - F5H4Z8
swissprot - B4DQH6
swissprot - P49746
swissprot - Q2HIZ1
Ensembl - ENSG00000169231
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1L8P7ENSDARG00000012060Danio rerio
 thbs3aENSDARG00000077641Danio rerio
 Thbs3ENSMUSG00000028047Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
THBS4 / P35443 / thrombospondin 4ENSG0000011329661
COMP / P49747 / cartilage oligomeric matrix proteinENSG0000010566450
THBS1 / P07996 / thrombospondin 1ENSG0000013780142
THBS2 / P35442 / thrombospondin 2ENSG0000018634042


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR003367  Thrombospondin, type 3-like repeat
 IPR008859  Thrombospondin, C-terminal
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017897  Thrombospondin, type 3 repeat
 IPR018097  EGF-like calcium-binding, conserved site
 IPR024665  Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain
 IPR028507  Thrombospondin-3
 IPR028974  TSP type-3 repeat
 IPR037349  Thrombospondin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003417 growth plate cartilage development IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion NAS
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0043931 ossification involved in bone maturation IEA
 biological_processGO:0060346 bone trabecula formation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Signaling by PDGF


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100311 PDGFB / P01127 / platelet derived growth factor subunit B  / reaction / complex
 ENSG00000197461 PDGFA / P04085 / platelet derived growth factor subunit A  / complex / reaction






 

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