ENSG00000170454


Homo sapiens

Features
Gene ID: ENSG00000170454
  
Biological name :KRT75
  
Synonyms : keratin 75 / KRT75 / O95678
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.13
Gene start: 52424070
Gene end: 52434525
  
Corresponding Affymetrix probe sets: 207065_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000252245
NCBI entrez gene - 9119     See in Manteia.
OMIM - 609025
RefSeq - NM_004693
RefSeq Peptide - NP_004684
swissprot - O95678
Ensembl - ENSG00000170454
  
Related genetic diseases (OMIM): 612318 - {Pseudofolliculitis barbae, susceptibility to}, 612318
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 krt4ENSDARG00000017624Danio rerio
 krt5ENSDARG00000058371Danio rerio
 krt8ENSDARG00000058358Danio rerio
 zgc:158846ENSDARG00000058462Danio rerio
 ENSGALG00000043689Gallus gallus
 KRT5ENSGALG00000032672Gallus gallus
 KRT6AENSGALG00000030629Gallus gallus
 KRT75ENSGALG00000035972Gallus gallus
 Krt75ENSMUSG00000022986Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KRT5 / P13647 / keratin 5ENSG0000018608179
KRT6A / P02538 / keratin 6AENSG0000020542074
KRT6C / P48668 / keratin 6CENSG0000017046573
KRT6B / P04259 / keratin 6BENSG0000018547973
KRT3 / P12035 / keratin 3ENSG0000018644263
KRT76 / Q01546 / keratin 76ENSG0000018506962
KRT1 / P04264 / keratin 1ENSG0000016776861
KRT79 / Q5XKE5 / keratin 79ENSG0000018564060
KRT4 / P19013 / keratin 4ENSG0000017047758
KRT71 / Q3SY84 / keratin 71ENSG0000013964855
KRT8 / P05787 / keratin 8ENSG0000017042154
KRT7 / P08729 / keratin 7ENSG0000013548054


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR003054  Keratin, type II
 IPR018039  Intermediate filament protein, conserved site
 IPR032444  Keratin type II head


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0031424 keratinization TAS
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005882 intermediate filament IDA
 cellular_componentGO:0045095 keratin filament IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005198 structural molecule activity TAS


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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