ENSG00000173213


Homo sapiens

Features
Gene ID: ENSG00000173213
  
Biological name :TUBB8P12
  
Synonyms : A6NNZ2 / TUBB8P12 / tubulin beta 8 pseudogene 12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: p11.32
Gene start: 47390
Gene end: 49557
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000496713
NCBI entrez gene - 260334     See in Manteia.
swissprot - A6NNZ2
Ensembl - ENSG00000173213
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TUBB8 / Q3ZCM7 / tubulin beta 8 class VIIIENSG0000026145696
P68371 / TUBB4B / tubulin beta 4B class IVbENSG0000018822989
P04350 / TUBB4A / tubulin beta 4A class IVaENSG0000010483388
Q9BVA1 / TUBB2B / tubulin beta 2B class IIbENSG0000013728587
TUBB / P07437 / tubulin beta class IENSG0000019623087
Q13885 / TUBB2A / tubulin beta 2A class IIaENSG0000013726787
TUBB3 / Q13509 / tubulin beta 3 class IIIENSG0000025894785
TUBB6 / Q9BUF5 / tubulin beta 6 class VENSG0000017601484
AC092143.1ENSG0000019821182
TUBB1 / Q9H4B7 / tubulin beta 1 class VIENSG0000010116275
TUBE1 / Q9UJT0 / tubulin epsilon 1ENSG0000007493533
TUBD1 / Q9UJT1 / tubulin delta 1ENSG0000010842324
MC1R / Q01726 / melanocortin 1 receptorENSG000002588391


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002453  Beta tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR013838  Beta tubulin, autoregulation binding site
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain
 IPR036525  Tubulin/FtsZ, GTPase domain superfamily
 IPR037103  Tubulin/FtsZ, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007017 microtubule-based process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Recruitment of NuMA to mitotic centrosomes
Recycling pathway of L1
Cilium Assembly
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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