ENSG00000179403


Homo sapiens

Features
Gene ID: ENSG00000179403
  
Biological name :VWA1
  
Synonyms : Q6PCB0 / von Willebrand factor A domain containing 1 / VWA1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.33
Gene start: 1434861
Gene end: 1442882
  
Corresponding Affymetrix probe sets: 218731_s_at (Human Genome U133 Plus 2.0 Array)   222723_at (Human Genome U133 Plus 2.0 Array)   222724_at (Human Genome U133 Plus 2.0 Array)   225983_s_at (Human Genome U133 Plus 2.0 Array)   228651_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417185
Ensembl peptide - ENSP00000423404
Ensembl peptide - ENSP00000463643
Ensembl peptide - ENSP00000464343
NCBI entrez gene - 64856     See in Manteia.
OMIM - 611901
RefSeq - NM_199121
RefSeq - NM_022834
RefSeq Peptide - NP_073745
RefSeq Peptide - NP_954572
swissprot - Q6PCB0
swissprot - J3QLP3
swissprot - J3QRR0
Ensembl - ENSG00000179403
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vwa1ENSDARG00000075468Danio rerio
 VWA1ENSGALG00000001527Gallus gallus
 Vwa1ENSMUSG00000042116Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MATN2 / O00339 / matrilin 2ENSG0000013256123
MATN4 / O95460 / matrilin 4ENSG0000012415921
MATN1 / P21941 / matrilin 1, cartilage matrix proteinENSG0000016251020
MATN3 / O15232 / matrilin 3ENSG0000013203117
CD93 / Q9NPY3 / CD93 moleculeENSG0000012581011
CD248 / Q9HCU0 / CD248 moleculeENSG000001748079
THBD / P07204 / thrombomodulinENSG000001787269
Q8IWY4 / SCUBE1 / signal peptide, CUB domain and EGF like domain containing 1ENSG000001593079
Q9NQ36 / SCUBE2 / signal peptide, CUB domain and EGF like domain containing 2ENSG000001753569
Q8IX30 / SCUBE3 / signal peptide, CUB domain and EGF like domain containing 3ENSG000001461979
Q86T13 / CLEC14A / C-type lectin domain containing 14AENSG000001764355


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0048266 behavioral response to pain IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005614 interstitial matrix IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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