ENSG00000179632


Homo sapiens

Features
Gene ID: ENSG00000179632
  
Biological name :MAF1
  
Synonyms : MAF1 / MAF1 homolog, negative regulator of RNA polymerase III / Q9H063
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q24.3
Gene start: 144104499
Gene end: 144107611
  
Corresponding Affymetrix probe sets: 222998_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436639
Ensembl peptide - ENSP00000431907
Ensembl peptide - ENSP00000436720
Ensembl peptide - ENSP00000433979
Ensembl peptide - ENSP00000436030
Ensembl peptide - ENSP00000318604
NCBI entrez gene - 84232     See in Manteia.
OMIM - 610210
RefSeq - XM_017013904
RefSeq - NM_032272
RefSeq - XM_017013903
RefSeq Peptide - NP_115648
swissprot - H0YEV4
swissprot - E9PSH4
swissprot - Q9H063
swissprot - E9PR76
swissprot - E9PJ05
Ensembl - ENSG00000179632
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:112356ENSDARG00000036489Danio rerio
 Maf1ENSMUSG00000022553Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015257  Repressor of RNA polymerase III transcription Maf1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016480 negative regulation of transcription by RNA polymerase III IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0060077 inhibitory synapse IEA
 molecular_functionGO:0000994 RNA polymerase III core binding IBA
 molecular_functionGO:0001030 RNA polymerase III type 1 promoter DNA binding IDA
 molecular_functionGO:0001031 RNA polymerase III type 2 promoter DNA binding IDA
 molecular_functionGO:0001032 RNA polymerase III type 3 promoter DNA binding IDA
 molecular_functionGO:0050811 GABA receptor binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000083750 RRAGB / Q5VZM2 / Ras related GTP binding B  / reaction
 ENSG00000106615 RHEB / Q15382 / Ras homolog, mTORC1 binding  / reaction
 ENSG00000167965 MLST8 / Q9BVC4 / MTOR associated protein, LST8 homolog  / reaction
 ENSG00000141564 RPTOR / Q8N122 / regulatory associated protein of MTOR complex 1  / reaction
 ENSG00000177058 Q8NBW4 / SLC38A9 / solute carrier family 38 member 9  / reaction
 ENSG00000198793 MTOR / P42345 / mechanistic target of rapamycin kinase  / reaction
 ENSG00000025039 RRAGD / Q9NQL2 / Ras related GTP binding D  / reaction
 ENSG00000116954 RRAGC / Q9HB90 / Ras related GTP binding C  / reaction
 ENSG00000155876 RRAGA / Q7L523 / Ras related GTP binding A  / reaction






 

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