ENSG00000177058


Homo sapiens

Features
Gene ID: ENSG00000177058
  
Biological name :SLC38A9
  
Synonyms : Q8NBW4 / SLC38A9 / solute carrier family 38 member 9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q11.2
Gene start: 55625845
Gene end: 55773194
  
Corresponding Affymetrix probe sets: 235241_at (Human Genome U133 Plus 2.0 Array)   242330_at (Human Genome U133 Plus 2.0 Array)   243709_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420934
Ensembl peptide - ENSP00000397429
Ensembl peptide - ENSP00000420950
Ensembl peptide - ENSP00000427707
Ensembl peptide - ENSP00000427624
Ensembl peptide - ENSP00000427335
Ensembl peptide - ENSP00000426925
Ensembl peptide - ENSP00000426413
Ensembl peptide - ENSP00000425842
Ensembl peptide - ENSP00000425259
Ensembl peptide - ENSP00000425055
Ensembl peptide - ENSP00000424918
Ensembl peptide - ENSP00000424271
Ensembl peptide - ENSP00000423219
Ensembl peptide - ENSP00000422843
Ensembl peptide - ENSP00000316596
Ensembl peptide - ENSP00000380074
NCBI entrez gene - 153129     See in Manteia.
OMIM - 616203
RefSeq - XM_017009082
RefSeq - NM_001258286
RefSeq - NM_001258287
RefSeq - NM_001282429
RefSeq - NM_173514
RefSeq - XM_006714537
RefSeq - XM_006714538
RefSeq - XM_006714539
RefSeq - XM_011543173
RefSeq - XM_011543174
RefSeq - XM_011543176
RefSeq - XM_011543177
RefSeq - XM_011543178
RefSeq - XM_011543180
RefSeq - XM_011543182
RefSeq - XM_011543183
RefSeq - XM_011543184
RefSeq - XM_017009077
RefSeq - XM_017009078
RefSeq - XM_017009079
RefSeq - XM_017009080
RefSeq - XM_017009081
RefSeq Peptide - NP_001336313
RefSeq Peptide - NP_775785
RefSeq Peptide - NP_001245215
RefSeq Peptide - NP_001245216
RefSeq Peptide - NP_001269358
RefSeq Peptide - NP_001336311
RefSeq Peptide - NP_001336312
swissprot - D6RDH2
swissprot - D6RBB9
swissprot - D6R9X0
swissprot - E7ESU6
swissprot - B3KVK8
swissprot - Q8NBW4
swissprot - A0A024QZR9
swissprot - D6R9Q7
swissprot - D6RIW7
swissprot - D6RHW0
swissprot - D6RHF5
swissprot - D6RG31
swissprot - D6RER8
swissprot - D6RE72
Ensembl - ENSG00000177058
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q08BA4ENSDARG00000032769Danio rerio
 SLC38A9ENSGALG00000014712Gallus gallus
 Q8BGD6ENSMUSG00000047789Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013057  Amino acid transporter, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003333 amino acid transmembrane transport IDA
 biological_processGO:0006865 amino acid transport IEA
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0032008 positive regulation of TOR signaling IDA
 biological_processGO:0071230 cellular response to amino acid stimulus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0071986 Ragulator complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015171 amino acid transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
Macroautophagy
mTOR signalling
mTORC1-mediated signalling
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000023287 Q8TDY2 / RB1CC1 / RB1 inducible coiled-coil 1  / reaction / complex
 ENSG00000111725 PRKAB1 / Q9Y478 / protein kinase AMP-activated non-catalytic subunit beta 1  / reaction
 ENSG00000131791 O43741 / PRKAB2 / protein kinase AMP-activated non-catalytic subunit beta 2  / reaction
 ENSG00000115592 PRKAG3 / Q9UGI9 / protein kinase AMP-activated non-catalytic subunit gamma 3  / reaction
 ENSG00000083750 RRAGB / Q5VZM2 / Ras related GTP binding B  / complex / reaction
 ENSG00000106615 RHEB / Q15382 / Ras homolog, mTORC1 binding  / reaction / complex
 ENSG00000167965 MLST8 / Q9BVC4 / MTOR associated protein, LST8 homolog  / reaction / complex
 ENSG00000106617 PRKAG2 / Q9UGJ0 / protein kinase AMP-activated non-catalytic subunit gamma 2  / reaction
 ENSG00000141564 RPTOR / Q8N122 / regulatory associated protein of MTOR complex 1  / reaction / complex
 ENSG00000132356 PRKAA1 / Q13131 / protein kinase AMP-activated catalytic subunit alpha 1  / reaction
 ENSG00000181929 P54619 / PRKAG1 / protein kinase AMP-activated non-catalytic subunit gamma 1  / reaction
 ENSG00000123395 ATG101 / Q9BSB4 / autophagy related 101  / reaction / complex
 ENSG00000204673 AKT1S1 / Q96B36 / AKT1 substrate 1  / complex / reaction
 ENSG00000177169 ULK1 / O75385 / unc-51 like autophagy activating kinase 1  / complex / reaction
 ENSG00000175224 ATG13 / O75143 / autophagy related 13  / complex / reaction
 ENSG00000179632 MAF1 / Q9H063 / MAF1 homolog, negative regulator of RNA polymerase III  / reaction
 ENSG00000142208 AKT1 / P31749 / AKT serine/threonine kinase 1  / reaction
 ENSG00000166913 YWHAB / P31946 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta  / reaction / complex
 ENSG00000198793 MTOR / P42345 / mechanistic target of rapamycin kinase  / complex / reaction
 ENSG00000025039 RRAGD / Q9NQL2 / Ras related GTP binding D  / reaction / complex
 ENSG00000116954 RRAGC / Q9HB90 / Ras related GTP binding C  / complex / reaction
 ENSG00000162409 P54646 / PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2  / reaction
 ENSG00000155876 RRAGA / Q7L523 / Ras related GTP binding A  / complex / reaction






 

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