ENSG00000175224


Homo sapiens

Features
Gene ID: ENSG00000175224
  
Biological name :ATG13
  
Synonyms : ATG13 / autophagy related 13 / O75143
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p11.2
Gene start: 46617527
Gene end: 46674818
  
Corresponding Affymetrix probe sets: 203363_s_at (Human Genome U133 Plus 2.0 Array)   203364_s_at (Human Genome U133 Plus 2.0 Array)   209021_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463998
Ensembl peptide - ENSP00000463808
Ensembl peptide - ENSP00000464091
Ensembl peptide - ENSP00000464274
Ensembl peptide - ENSP00000352500
Ensembl peptide - ENSP00000378919
Ensembl peptide - ENSP00000431877
Ensembl peptide - ENSP00000431974
Ensembl peptide - ENSP00000432412
Ensembl peptide - ENSP00000433543
Ensembl peptide - ENSP00000433756
Ensembl peptide - ENSP00000434125
Ensembl peptide - ENSP00000434390
Ensembl peptide - ENSP00000436174
Ensembl peptide - ENSP00000436931
Ensembl peptide - ENSP00000437191
Ensembl peptide - ENSP00000462167
Ensembl peptide - ENSP00000462644
Ensembl peptide - ENSP00000463550
NCBI entrez gene - 9776     See in Manteia.
OMIM - 615088
RefSeq - XM_017018622
RefSeq - NM_001142673
RefSeq - NM_001205119
RefSeq - NM_001205120
RefSeq - NM_001205121
RefSeq - NM_001205122
RefSeq - NM_014741
RefSeq - XM_005253262
RefSeq - XM_005253263
RefSeq - XM_005253265
RefSeq - XM_005253266
RefSeq - XM_005253268
RefSeq - XM_006718394
RefSeq - XM_006718395
RefSeq - XM_006718396
RefSeq - XM_011520493
RefSeq - XM_011520496
RefSeq - XM_011520499
RefSeq - XM_011520500
RefSeq - XM_011520501
RefSeq - XM_011520502
RefSeq - XM_011520503
RefSeq - XM_017018599
RefSeq - XM_017018600
RefSeq - XM_017018601
RefSeq - XM_017018602
RefSeq - XM_017018603
RefSeq - XM_017018604
RefSeq - XM_017018605
RefSeq - XM_017018606
RefSeq - XM_017018607
RefSeq - XM_017018608
RefSeq - XM_017018609
RefSeq - XM_017018610
RefSeq - XM_017018611
RefSeq - XM_017018612
RefSeq - XM_017018613
RefSeq - XM_017018614
RefSeq - XM_017018615
RefSeq - XM_017018616
RefSeq - XM_017018617
RefSeq - XM_017018618
RefSeq - XM_017018619
RefSeq - XM_017018620
RefSeq - XM_017018621
RefSeq Peptide - NP_001333271
RefSeq Peptide - NP_001333275
RefSeq Peptide - NP_001333277
RefSeq Peptide - NP_001333278
RefSeq Peptide - NP_001333279
RefSeq Peptide - NP_001333280
RefSeq Peptide - NP_001333249
RefSeq Peptide - NP_001333250
RefSeq Peptide - NP_001333251
RefSeq Peptide - NP_001333252
RefSeq Peptide - NP_001333253
RefSeq Peptide - NP_001333254
RefSeq Peptide - NP_001333255
RefSeq Peptide - NP_001333256
RefSeq Peptide - NP_001333257
RefSeq Peptide - NP_001333258
RefSeq Peptide - NP_001333259
RefSeq Peptide - NP_001333260
RefSeq Peptide - NP_001333261
RefSeq Peptide - NP_001333273
RefSeq Peptide - NP_001333281
RefSeq Peptide - NP_001333282
RefSeq Peptide - NP_001333283
RefSeq Peptide - NP_055556
RefSeq Peptide - NP_001136145
RefSeq Peptide - NP_001192048
RefSeq Peptide - NP_001192049
RefSeq Peptide - NP_001192050
RefSeq Peptide - NP_001192051
RefSeq Peptide - NP_001333240
RefSeq Peptide - NP_001333241
RefSeq Peptide - NP_001333242
RefSeq Peptide - NP_001333243
RefSeq Peptide - NP_001333244
RefSeq Peptide - NP_001333245
RefSeq Peptide - NP_001333248
swissprot - E9PPR2
swissprot - H0YCL5
swissprot - H0YDR0
swissprot - H0YEM7
swissprot - H0YF43
swissprot - J3KRU6
swissprot - J3KST9
swissprot - J3QLH7
swissprot - J3QR16
swissprot - J3QR83
swissprot - J3QRL1
swissprot - J9JIF6
swissprot - O75143
swissprot - A0A1B0GXJ3
Ensembl - ENSG00000175224
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atg13ENSDARG00000036040Danio rerio
 ATG13ENSGALG00000008347Gallus gallus
 Atg13ENSMUSG00000027244Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018731  Autophagy-related protein 13


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IEA
 biological_processGO:0000423 mitophagy IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0098780 response to mitochondrial depolarisation IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0000407 phagophore assembly site ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:1990316 Atg1/ULK1 kinase complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000023287 Q8TDY2 / RB1CC1 / RB1 inducible coiled-coil 1  / complex
 ENSG00000111725 PRKAB1 / Q9Y478 / protein kinase AMP-activated non-catalytic subunit beta 1  / reaction / complex
 ENSG00000131791 O43741 / PRKAB2 / protein kinase AMP-activated non-catalytic subunit beta 2  / reaction / complex
 ENSG00000115592 PRKAG3 / Q9UGI9 / protein kinase AMP-activated non-catalytic subunit gamma 3  / reaction / complex
 ENSG00000083750 RRAGB / Q5VZM2 / Ras related GTP binding B  / complex / reaction
 ENSG00000106615 RHEB / Q15382 / Ras homolog, mTORC1 binding  / complex / reaction
 ENSG00000167965 MLST8 / Q9BVC4 / MTOR associated protein, LST8 homolog  / complex / reaction
 ENSG00000106617 PRKAG2 / Q9UGJ0 / protein kinase AMP-activated non-catalytic subunit gamma 2  / reaction / complex
 ENSG00000141564 RPTOR / Q8N122 / regulatory associated protein of MTOR complex 1  / complex / reaction
 ENSG00000132356 PRKAA1 / Q13131 / protein kinase AMP-activated catalytic subunit alpha 1  / reaction / complex
 ENSG00000181929 P54619 / PRKAG1 / protein kinase AMP-activated non-catalytic subunit gamma 1  / complex / reaction
 ENSG00000177169 ULK1 / O75385 / unc-51 like autophagy activating kinase 1  / complex
 ENSG00000177058 Q8NBW4 / SLC38A9 / solute carrier family 38 member 9  / complex / reaction
 ENSG00000078142 PIK3C3 / Q8NEB9 / phosphatidylinositol 3-kinase catalytic subunit type 3  / reaction
 ENSG00000126581 BECN1 / Q14457 / beclin 1  / reaction
 ENSG00000088986 DYNLL1 / P63167 / dynein light chain LC8-type 1  / reaction
 ENSG00000162409 P54646 / PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2  / complex / reaction
 ENSG00000155876 RRAGA / Q7L523 / Ras related GTP binding A  / reaction / complex
 ENSG00000123395 ATG101 / Q9BSB4 / autophagy related 101  / complex
 ENSG00000110497 AMBRA1 / Q9C0C7 / autophagy and beclin 1 regulator 1  / reaction
 ENSG00000126775 ATG14 / Q6ZNE5 / autophagy related 14  / reaction
 ENSG00000198793 MTOR / P42345 / mechanistic target of rapamycin kinase  / reaction / complex
 ENSG00000025039 RRAGD / Q9NQL2 / Ras related GTP binding D  / reaction / complex
 ENSG00000264364 DYNLL2 / Q96FJ2 / dynein light chain LC8-type 2  / reaction
 ENSG00000116954 RRAGC / Q9HB90 / Ras related GTP binding C  / reaction / complex
 ENSG00000196455 PIK3R4 / Q99570 / phosphoinositide-3-kinase regulatory subunit 4  / reaction






 

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