ENSG00000179709


Homo sapiens

Features
Gene ID: ENSG00000179709
  
Biological name :NLRP8
  
Synonyms : NLR family pyrin domain containing 8 / NLRP8 / Q86W28
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.43
Gene start: 55947832
Gene end: 55988629
  
Corresponding Affymetrix probe sets: 1553526_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000291971
Ensembl peptide - ENSP00000468121
NCBI entrez gene - 126205     See in Manteia.
OMIM - 609659
RefSeq - NM_001317000
RefSeq - NM_176811
RefSeq Peptide - NP_001303929
RefSeq Peptide - NP_789781
swissprot - Q86W28
Ensembl - ENSG00000179709
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO704635.1ENSDARG00000105141Danio rerio
 nlrb5ENSDARG00000090699Danio rerio
 si:ch211-66k16.2ENSDARG00000095634Danio rerio
 si:ch211-66k16.28ENSDARG00000088423Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLRP14 / Q86W24 / NLR family pyrin domain containing 14ENSG0000015807734
NLRP12 / P59046 / NLR family pyrin domain containing 12ENSG0000014240531
NLRP13 / Q86W25 / NLR family pyrin domain containing 13ENSG0000017357230
NLRP9 / Q7RTR0 / NLR family pyrin domain containing 9ENSG0000018579230
NLRP4 / Q96MN2 / NLR family pyrin domain containing 4ENSG0000016050530
NLRP3 / Q96P20 / NLR family pyrin domain containing 3ENSG0000016271129
NLRP2 / Q9NX02 / NLR family pyrin domain containing 2ENSG0000002255628
NLRP5 / P59047 / NLR family pyrin domain containing 5ENSG0000017148728
NLRP7 / Q8WX94 / NLR family pyrin domain containing 7ENSG0000016763428
NLRP1 / Q9C000 / NLR family pyrin domain containing 1ENSG0000009159225
NLRP11 / P59045 / NLR family pyrin domain containing 11ENSG0000017987324
NLRP6 / P59044 / NLR family pyrin domain containing 6ENSG0000017488520
NLRP10 / Q86W26 / NLR family pyrin domain containing 10ENSG0000018226113
RNH1 / P13489 / ribonuclease/angiogenin inhibitor 1ENSG0000002319110


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR004020  DAPIN domain
 IPR007111  NACHT nucleoside triphosphatase
 IPR011029  Death-like domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0070997 neuron death IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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