ENSG00000185792


Homo sapiens

Features
Gene ID: ENSG00000185792
  
Biological name :NLRP9
  
Synonyms : NLR family pyrin domain containing 9 / NLRP9 / Q7RTR0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.42
Gene start: 55708432
Gene end: 55738402
  
Corresponding Affymetrix probe sets: 1553527_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465253
Ensembl peptide - ENSP00000331857
NCBI entrez gene - 338321     See in Manteia.
OMIM - 609663
RefSeq - NM_176820
RefSeq Peptide - NP_789790
swissprot - Q7RTR0
Ensembl - ENSG00000185792
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO704635.1ENSDARG00000105141Danio rerio
 nlrb5ENSDARG00000090699Danio rerio
 si:ch211-66k16.2ENSDARG00000095634Danio rerio
 si:ch211-66k16.28ENSDARG00000088423Danio rerio
 Nlrp9aENSMUSG00000054102Mus musculus
 Nlrp9bENSMUSG00000060508Mus musculus
 Nlrp9cENSMUSG00000040614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLRP4 / Q96MN2 / NLR family pyrin domain containing 4ENSG0000016050541
NLRP14 / Q86W24 / NLR family pyrin domain containing 14ENSG0000015807739
NLRP13 / Q86W25 / NLR family pyrin domain containing 13ENSG0000017357233
NLRP12 / P59046 / NLR family pyrin domain containing 12ENSG0000014240533
NLRP11 / P59045 / NLR family pyrin domain containing 11ENSG0000017987333
NLRP2 / Q9NX02 / NLR family pyrin domain containing 2ENSG0000002255632
NLRP3 / Q96P20 / NLR family pyrin domain containing 3ENSG0000016271132
NLRP5 / P59047 / NLR family pyrin domain containing 5ENSG0000017148732
NLRP8 / Q86W28 / NLR family pyrin domain containing 8ENSG0000017970931
NLRP7 / Q8WX94 / NLR family pyrin domain containing 7ENSG0000016763430
NLRP1 / Q9C000 / NLR family pyrin domain containing 1ENSG0000009159229
NLRP6 / P59044 / NLR family pyrin domain containing 6ENSG0000017488523
NLRP10 / Q86W26 / NLR family pyrin domain containing 10ENSG0000018226116
RNH1 / P13489 / ribonuclease/angiogenin inhibitor 1ENSG0000002319113


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR004020  DAPIN domain
 IPR007111  NACHT nucleoside triphosphatase
 IPR011029  Death-like domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0032741 positive regulation of interleukin-18 production ISS
 biological_processGO:0045087 innate immune response ISS
 biological_processGO:0051607 defense response to virus ISS
 biological_processGO:0070269 pyroptosis ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0061702 inflammasome complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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