ENSG00000182261


Homo sapiens

Features
Gene ID: ENSG00000182261
  
Biological name :NLRP10
  
Synonyms : NLR family pyrin domain containing 10 / NLRP10 / Q86W26
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.4
Gene start: 7959424
Gene end: 7965426
  
Corresponding Affymetrix probe sets: 1553534_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327763
Ensembl peptide - ENSP00000436255
NCBI entrez gene - 338322     See in Manteia.
OMIM - 609662
RefSeq - NM_176821
RefSeq - XM_011520043
RefSeq Peptide - NP_789791
swissprot - E9PPY0
swissprot - Q86W26
Ensembl - ENSG00000182261
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO704635.1ENSDARG00000105141Danio rerio
 nlrb5ENSDARG00000090699Danio rerio
 si:ch211-66k16.2ENSDARG00000095634Danio rerio
 si:ch211-66k16.28ENSDARG00000088423Danio rerio
 Nlrp10ENSMUSG00000049709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLRP3 / Q96P20 / NLR family pyrin domain containing 3ENSG0000016271135
NLRP12 / P59046 / NLR family pyrin domain containing 12ENSG0000014240535
NLRP1 / Q9C000 / NLR family pyrin domain containing 1ENSG0000009159229
NLRP14 / Q86W24 / NLR family pyrin domain containing 14ENSG0000015807729
NLRP6 / P59044 / NLR family pyrin domain containing 6ENSG0000017488527
NLRP4 / Q96MN2 / NLR family pyrin domain containing 4ENSG0000016050526
NLRP7 / Q8WX94 / NLR family pyrin domain containing 7ENSG0000016763425
NLRP9 / Q7RTR0 / NLR family pyrin domain containing 9ENSG0000018579225
NLRP5 / P59047 / NLR family pyrin domain containing 5ENSG0000017148724
NLRP13 / Q86W25 / NLR family pyrin domain containing 13ENSG0000017357224
NLRP2 / Q9NX02 / NLR family pyrin domain containing 2ENSG0000002255624
NLRP8 / Q86W28 / NLR family pyrin domain containing 8ENSG0000017970922
NLRP11 / P59045 / NLR family pyrin domain containing 11ENSG0000017987320
RNH1 / P13489 / ribonuclease/angiogenin inhibitor 1ENSG000000231912


Protein motifs (from Interpro)
Interpro ID Name
 IPR004020  DAPIN domain
 IPR007111  NACHT nucleoside triphosphatase
 IPR011029  Death-like domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002827 positive regulation of T-helper 1 type immune response IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050717 positive regulation of interleukin-1 alpha secretion IMP
 biological_processGO:0050729 positive regulation of inflammatory response IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IMP
 biological_processGO:0050832 defense response to fungus IEA
 biological_processGO:1900426 positive regulation of defense response to bacterium IMP
 biological_processGO:2000318 positive regulation of T-helper 17 type immune response IEA
 biological_processGO:2000484 positive regulation of interleukin-8 secretion IMP
 biological_processGO:2000778 positive regulation of interleukin-6 secretion IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IDA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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