ENSG00000180628


Homo sapiens

Features
Gene ID: ENSG00000180628
  
Biological name :PCGF5
  
Synonyms : PCGF5 / polycomb group ring finger 5 / Q86SE9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.32
Gene start: 91163012
Gene end: 91284331
  
Corresponding Affymetrix probe sets: 226326_at (Human Genome U133 Plus 2.0 Array)   227935_s_at (Human Genome U133 Plus 2.0 Array)   229194_at (Human Genome U133 Plus 2.0 Array)   229996_s_at (Human Genome U133 Plus 2.0 Array)   235331_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000337500
Ensembl peptide - ENSP00000445704
Ensembl peptide - ENSP00000479492
NCBI entrez gene - 84333     See in Manteia.
OMIM - 617407
RefSeq - XM_017016778
RefSeq - NM_001256549
RefSeq - NM_001257101
RefSeq - NM_032373
RefSeq - XM_011540271
RefSeq - XM_011540272
RefSeq - XM_017016776
RefSeq - XM_017016777
RefSeq - XM_006718030
RefSeq Peptide - NP_001244030
RefSeq Peptide - NP_115749
RefSeq Peptide - NP_001243478
swissprot - Q86SE9
Ensembl - ENSG00000180628
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B3DK16ENSDARG00000071007Danio rerio
 pcgf5bENSDARG00000052388Danio rerio
 PCGF5ENSGALG00000006502Gallus gallus
 Pcgf5ENSMUSG00000024805Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PCGF3 / Q3KNV8 / polycomb group ring finger 3ENSG0000018561942
PCGF6 / Q9BYE7 / polycomb group ring finger 6ENSG0000015637433
PCGF1 / Q9BSM1 / polycomb group ring finger 1ENSG0000011528932
PCGF2 / P35227 / polycomb group ring finger 2ENSG0000027725831
BMI1 / P35226 / BMI1 proto-oncogene, polycomb ring fingerENSG0000016828329
COMMD3-BMI1 / COMMD3-BMI1 readthroughENSG0000026989729


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR032443  RAWUL domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0036353 histone H2A-K119 monoubiquitination ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0060819 inactivation of X chromosome by genetic imprinting ISS
 cellular_componentGO:0000805 X chromosome ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0031519 PcG protein complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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