ENSG00000181218


Homo sapiens

Features
Gene ID: ENSG00000181218
  
Biological name :HIST3H2A
  
Synonyms : HIST3H2A / histone cluster 3 H2A / Q7L7L0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q42.13
Gene start: 228456979
Gene end: 228457873
  
Corresponding Affymetrix probe sets: 221582_at (Human Genome U133 Plus 2.0 Array)   231681_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355656
NCBI entrez gene - 92815     See in Manteia.
OMIM - 615015
RefSeq - NM_033445
RefSeq Peptide - NP_254280
swissprot - Q7L7L0
Ensembl - ENSG00000181218
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8BFU2ENSMUSG00000078851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q93077 / HIST1H2AC / histone cluster 1 H2A family member cENSG0000018057399
Q6FI13 / HIST2H2AA3 / histone cluster 2 H2A family member a3ENSG0000020381298
P0C0S8 / HIST1H2AK / histone cluster 1 H2A family member kENSG0000027522198
Q6FI13 / HIST2H2AA4 / histone cluster 2 H2A family member a4ENSG0000027219698
P0C0S8 / HIST1H2AG / histone cluster 1 H2A family member gENSG0000019678798
P0C0S8 / HIST1H2AI / histone cluster 1 H2A family member iENSG0000019674798
P0C0S8 / HIST1H2AM / histone cluster 1 H2A family member mENSG0000027867798
P0C0S8 / HIST1H2AL / histone cluster 1 H2A family member lENSG0000027690398
P20671 / HIST1H2AD / histone cluster 1 H2A family member dENSG0000019686698
AL031777.3ENSG0000028298898
Q96KK5 / HIST1H2AH / histone cluster 1 H2A family member hENSG0000027499796
Q16777 / HIST2H2AC / histone cluster 2 H2A family member cENSG0000018426096
Q99878 / HIST1H2AJ / histone cluster 1 H2A family member jENSG0000027636895
Q8IUE6 / HIST2H2AB / histone cluster 2 H2A family member bENSG0000018427095
Q96QV6 / HIST1H2AA / histone cluster 1 H2A family member aENSG0000016450893
H2AFJ / Q9BTM1 / H2A histone family member JENSG0000024670592
H2AFX / P16104 / H2A histone family member XENSG0000018848691
H2AFY2 / Q9P0M6 / H2A histone family member Y2ENSG0000009928465
H2AFY / O75367 / H2A histone family member YENSG0000011364865
H2AFB3 / P0C5Z0 / H2A histone family member B3ENSG0000027774538


Protein motifs (from Interpro)
Interpro ID Name
 IPR002119  Histone H2A
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold
 IPR032454  Histone H2A, C-terminal domain
 IPR032458  Histone H2A conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006337 nucleosome disassembly IMP
 biological_processGO:0006342 chromatin silencing IBA
 biological_processGO:0070914 UV-damage excision repair IMP
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0000788 nuclear nucleosome IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones
HATs acetylate histones
RMTs methylate histone arginines
UCH proteinases
Ub-specific processing proteases
Metalloprotease DUBs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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